Madrid-Zaragoza-Irun-Bordeaux-Tours-Paris is 1400 Km according to Google maps. That's 4 hours at 350 Km/h [though I'm not counting the stops]. It would blow all but low-cost flights out of the water, because of the time to get to/from the airports at either end, and the waiting times at check-in and baggage collection. "It's the statue, man, The Statue."
As things stand, Zaragoza to Pamplona will be a partial high-speed line, the rest in direction of San Sebastián less certain, while the main route towards Irún will be through the Guadarrama tunnel to Valladolid, across Burgos to Vitoria, then on the Basque Y ("Y Vasca") to Irún (altogether c. 530 km). Madrid to Irún will be c. 2h20m, the Paris to Bordeaux line (535 km), if all ready by 2016, is promised at 2h10m, a Bordeaux-Dax-border line (235 km) could be done in one hour, that would add up to 5h30m. But 350 km/h and non-stop, 1300 km, even 3h50m would seem possible. *Lunatic*, n. One whose delusions are out of fashion.
Of course, politically, the Autonomous Community of Castilla-Leon would prefer to see Valladolid served first. I wouldn't be surprised if the connection between Burgos and the Basque Y takes a long while to be completed, especially if the PP is in the National government.
Valladolid would likely become a hub in any event, serving Madrid, Burgos-Vitoria, Galicia and Porto. "It's the statue, man, The Statue."
*Lunatic*, n. One whose delusions are out of fashion.