The Coolscan V comes with a feeder that will take 35mm film cut in the normal 6 frame strips, which is fine for me: I generally cut film to that length for storage anyway and my iMac can scan while I work or read ET or whatever. I can't work out from the website whether the 5000 shipped with one of those. I'd need to buy an accessory for scanning whole rolls. Actually, I'm not certain if I can even buy such an accessory for the V, which I think might be one of the reasons for the more "professional" price on the 5000. That and the 16-bit A/D convertor.