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Swine flu 'pandemic' declared - Health News, Health & Families - The Independent
The World Health Organization told its member nations it was declaring a swine flu pandemic today - the first global flu epidemic in 41 years - as infections climbed in the United States, Europe, Australia, South America and elsewhere.

In a statement sent to member countries, WHO said it decided to raise the pandemic warning level from phase 5 to 6 -- its highest alert -- after holding an emergency meeting on swine flu with its experts.

The long-awaited pandemic decision is scientific confirmation that a new flu virus has emerged and is quickly circling the globe. It will trigger drugmakers to speed up production of a swine flu vaccine and prompt governments to devote more money toward efforts to contain the virus.

"At this early stage, the pandemic can be characterized globally as being moderate in severity," WHO said in the statement, urging nations not to close borders or restrict travel and trade. "(We) remain in close dialogue with influenza vaccine manufacturers."

by Fran (fran at eurotrib dot com) on Thu Jun 11th, 2009 at 03:45:56 PM EST
[ Parent ]
The WHO news release is here. Since I find some of the dismissals on ET rather flippant and unscientific, I shall highlight some points in the release:

The virus is contagious, spreading easily from one person to another, and from one country to another. As of today, nearly 30,000 confirmed cases have been reported in 74 countries.

This is only part of the picture. With few exceptions, countries with large numbers of cases are those with good surveillance and testing procedures in place.

Spread in several countries can no longer be traced to clearly-defined chains of human-to-human transmission. Further spread is considered inevitable.

Something new about this strain of influenza -- its age pattern:

We know that the novel H1N1 virus preferentially infects younger people. In nearly all areas with large and sustained outbreaks, the majority of cases have occurred in people under the age of 25 years.

In some of these countries, around 2% of cases have developed severe illness, often with very rapid progression to life-threatening pneumonia.

Most cases of severe and fatal infections have been in adults between the ages of 30 and 50 years.

This pattern is significantly different from that seen during epidemics of seasonal influenza, when most deaths occur in frail elderly people.

As for those most in danger:

Without question, pregnant women are at increased risk of complications. This heightened risk takes on added importance for a virus, like this one, that preferentially infects younger age groups.

Finally, and perhaps of greatest concern, we do not know how this virus will behave under conditions typically found in the developing world. To date, the vast majority of cases have been detected and investigated in comparatively well-off countries.

Let me underscore two of many reasons for this concern. First, more than 99% of maternal deaths, which are a marker of poor quality care during pregnancy and childbirth, occurs in the developing world.

Second, around 85% of the burden of chronic diseases is concentrated in low- and middle-income countries.

Although the pandemic appears to have moderate severity in comparatively well-off countries, it is prudent to anticipate a bleaker picture as the virus spreads to areas with limited resources, poor health care, and a high prevalence of underlying medical problems.



*Lunatic*, n.
One whose delusions are out of fashion.
by DoDo on Fri Jun 12th, 2009 at 04:44:46 AM EST
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Most cases of severe and fatal infections have been in adults between the ages of 30 and 50 years.

This is the scary piece of data (and not only because I belong in that age group). It might mean that the influenza kills by triggering an overactive reaction in a person's own immune system, a so-called cytokine storm, and that means that being young and healthy might not help you out at all. It is how the flu of 1918 reportedly killed.

(Also, the first wave of the 1918 influenza in the spring was mild. It was the second and the third wave, after the virus had supposedly mutated, who were the killers. Now, it's of course completely possible and even perhaps probable, due to changed circumstances, that this virus won't mutate in that direction at all, and we might get a vaccine soon enough anyway. Still, I do not think this is just a case of fear-mongering, or completely unwarranted worry. I haven't followed the ET discussions on the flu though so I don't know what's been said...)

You have a normal feeling for a moment, then it passes. --More--

by tzt (tztmail at gmail dot com) on Fri Jun 12th, 2009 at 05:40:46 AM EST
[ Parent ]
The widespread view seemed to be that the warnings (1) served the interests of flu vaccine producers, (2) were severe only because the US was affected.

*Lunatic*, n.
One whose delusions are out of fashion.
by DoDo on Fri Jun 12th, 2009 at 05:50:51 AM EST
[ Parent ]
Ah. So the "Rumsfeld has stock in Tamiflu!" thing did not come up yet? :-p

You have a normal feeling for a moment, then it passes. --More--
by tzt (tztmail at gmail dot com) on Fri Jun 12th, 2009 at 05:52:42 AM EST
[ Parent ]
Novartis mit Schweinegrippe-Impfstoff - Aktie steigt auf Viermonatshoch | Top-News | News | CASHNovartis With pig influenza vaccine - share rose to four-month high | Top News | News | CASH

Novartis hat nach eigenen Angaben einen Impfstoff gegen die Schweinegrippe entwickelt. Klinische Studien sollen im Juli beginnen. Die Zulassung erwartet der Konzern gegen Ende Jahr.

Novartis has indicated that it has developeda vaccine against swine flu . Clinical studies will begin in July. The Group expects the approval toward the end of the year.
Die Produktion einer ersten Charge eines A(H1N1)-Impstoffs sei um Wochen früher abgeschlossen worden als erwartet, teilte der Konzern mit. Möglich gewesen sei dies dank der vom Unternehmen angewandten Herstellungsmethode auf der Basis von Zellkulturen statt wie sonst üblich auf Hühnerei-Basis.The production of a first batch of a (H1N1)-vaccine was finished weeks sooner than had been expected, the group announced. This was possible thanks to the company applying a production method based on cell cultures instead of the conventionally used chicken-egg base.
Die Aktie von Novartis erfuhr für ihre Verhältnisse einen deutlichen Aufschwung. Am Freitag stieg sie bis Mittag um 4 Prozent auf 44.75 Franken. Das ist das höchste Niveau seit Ende Februar.Shares of Novartis showed a significant raise. On Friday it rose towards lunchtime by 4 percent to 44.75 francs. This is the highest level since late February.
by Fran (fran at eurotrib dot com) on Fri Jun 12th, 2009 at 06:07:43 AM EST
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