Only in a region where the rivals have nuclear power capabilities.
I submit that is not the case. Israel is a nuclear power, yet I think you could easily argue that Iran, which is not a nuclear power, is a power player in the region for a variety of reasons, not the least of which being that their proximity to our bestest buddy, Saudi Arabia. Conservatives want live babies so they can raise them to be dead soldiers. - George Carlin
A regional rival with nuclear weapons is necessary for nuclear weapons to be a requisite of status as a regional power, not sufficient. I've been accused of being a Marxist, yet while Harpo's my favourite, it's Groucho I'm always quoting. Odd, that.