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Caloric Restriction Extends Life In Monkeys, Study Finds / Science News

A 20-year study found that Rhesus monkeys fed a nutritious, low-calorie diet have fewer age-related diseases than counterparts on a normal diet, researchers report July 10 in Science. Also, MRIs reveal less shrinking with age in areas important for decision-making and controlling movement in the brains of calorie-restricted animals, report Ricki Colman and Richard Weindruch, both of the Wisconsin National Primate Research Center at the University of Wisconsin-Madison, and colleagues.

These results show that calorie restriction helps preserve primates' bodies and brains, says Luigi Fontana, of Washington University in St. Louis and the Italian National Health Service in Rome. Calorie restriction has already been shown to extend the lifespan of mice and dogs, as well as yeast, fruit flies and worms.

The findings may have ramifications for fighting aging and disease in humans, Fontana says. "I'm confident that everything that happens in [non-human] primates will happen in humans." Since both groups of monkeys are on a very healthy diet, people who go from a high-fat Western diet to a healthy, restricted diet may experience even greater health benefits than seen in this study.



A man of words and not of deeds is like a garden full of weeds; a man of deeds and not of words is like a garden full of turds — Anonymous
by Migeru (migeru at eurotrib dot com) on Thu Jul 9th, 2009 at 12:22:25 PM EST
And the headline here:

Chicago Tribune: 1 in 4 Illinois adults is obese -- a record

The CDC found that in 2008 Illinois was among 32 states where 25 percent or more of adults were, to put it bluntly, fat. Officially, obesity counts as having a body mass index - a ratio of weight to height - of 30 percent or higher.

To put that in perspective, two decades ago no state counted more than 15 percent of adults as obese. That hurdle was passed in 1991 by four states, including Michigan.

In 1996, three states, including Indiana and Kentucky, passed the 20 percent mark. In 2001, Mississippi became the first state where at least 25 percent of adults were excessively heavy. Four years later, three states - Louisiana, Mississippi and West Virginia - topped 30 percent.

Illinois has never been the fattest state, but residents have been gaining girth along with the rest of the country.

In 1985, as far back as the current CDC report goes, fewer than 10 percent of Illinoisans were obese. Two years later, the figure jumped to 10 to 14 percent. In 1994, it rose again to the 15 to 19 percent range. Five years later, obesity rates in Illinois soared to 20 percent or more. Then, last year, rates climbed again, to the 25 to 29 percent range.

Frankly I'm surprised it isn't higher.


"Pretending that you already know the answer when you don't is not actually very helpful." ~Migeru.

by poemless on Thu Jul 9th, 2009 at 12:33:42 PM EST
[ Parent ]
Fortunately, the solution is obvious: Raise cigarette taxes again.

Conservatives want live babies so they can raise them to be dead soldiers. - George Carlin
by Drew J Jones (myfriends@thisispancakes.com) on Thu Jul 9th, 2009 at 12:47:37 PM EST
[ Parent ]
I like it!
by Colman (colman at eurotrib.com) on Thu Jul 9th, 2009 at 12:48:10 PM EST
[ Parent ]
It'd be funny if it didn't seem to work that way.

Conservatives want live babies so they can raise them to be dead soldiers. - George Carlin
by Drew J Jones (myfriends@thisispancakes.com) on Thu Jul 9th, 2009 at 12:52:54 PM EST
[ Parent ]
This is kind of silly, isn't it?  "Scientists discover eating non-shitty food makes you healthier."

Conservatives want live babies so they can raise them to be dead soldiers. - George Carlin
by Drew J Jones (myfriends@thisispancakes.com) on Thu Jul 9th, 2009 at 12:49:05 PM EST
[ Parent ]
Just as silly as "scientists discover smoking is bad for you".

In other words, the food industry can no longer hide behind "we just feed people what they ask for"...

A man of words and not of deeds is like a garden full of weeds; a man of deeds and not of words is like a garden full of turds — Anonymous

by Migeru (migeru at eurotrib dot com) on Thu Jul 9th, 2009 at 12:52:52 PM EST
[ Parent ]
Yeah, good luck with that.  As long as the typical American happily weighs more than a European car, the food companies have nothing to worry about.

This is, after all, the country in which the morbidly obese can sue airlines for charging them extra because they require two seats.  And win.

Conservatives want live babies so they can raise them to be dead soldiers. - George Carlin

by Drew J Jones (myfriends@thisispancakes.com) on Thu Jul 9th, 2009 at 12:57:21 PM EST
[ Parent ]
Can smokers sue airlines any longer for throwing them out of the plain if they light up?

A man of words and not of deeds is like a garden full of weeds; a man of deeds and not of words is like a garden full of turds — Anonymous
by Migeru (migeru at eurotrib dot com) on Thu Jul 9th, 2009 at 01:08:36 PM EST
[ Parent ]
No, but smoking is a choice.  Being fat and taking up half of my seat is not, for some reason.

(Note: Yes, I know for some people being fat is not a choice.  I submit, however, that they are an incredibly small minority.)

Conservatives want live babies so they can raise them to be dead soldiers. - George Carlin

by Drew J Jones (myfriends@thisispancakes.com) on Thu Jul 9th, 2009 at 01:12:57 PM EST
[ Parent ]
There is a big industry whose profits depend on super-sized portions. That's like the tobacco industry.

Tobacco is addictive and so is food and some people have metabolic issues, too...

Unlike with tobacco, there isn't a "passive eater"...

A man of words and not of deeds is like a garden full of weeds; a man of deeds and not of words is like a garden full of turds — Anonymous

by Migeru (migeru at eurotrib dot com) on Thu Jul 9th, 2009 at 01:44:18 PM EST
[ Parent ]
Unlike with tobacco, there isn't a "passive eater"...

Yes, hmmm, well, children usually get the diet of their parents, so there is some kind of secondary negative effect to poor diets, too.
by nanne (zwaerdenmaecker@gmail.com) on Thu Jul 9th, 2009 at 04:40:25 PM EST
[ Parent ]
Not to mention things like the higher cost of healthcare for everyone, the suffering of factory farmed animals, and the way we're killing the planet in order to protect the rights of Americans to consume as much as humanly possible...  

"Pretending that you already know the answer when you don't is not actually very helpful." ~Migeru.
by poemless on Thu Jul 9th, 2009 at 04:50:30 PM EST
[ Parent ]
Not necessarily on the health care.  The findings I've read on it actually suggest the obese and smokers are cheaper to society over their lifetimes than healthy people, due to the fact that they generally die much earlier.

I wouldn't base an opinion on those reports, and much of it probably depends on how much they nickel and dime each group, but I think, on balance, the evidence suggests that there's not an enormous difference in cost to society.  If anything, smokers and the obese may be a little cheaper.

The rest I agree with you on, although, really, I can't personally claim to be innocent in the "consume lots" department.  I'm sure I consume more than I should.

Conservatives want live babies so they can raise them to be dead soldiers. - George Carlin

by Drew J Jones (myfriends@thisispancakes.com) on Thu Jul 9th, 2009 at 05:32:34 PM EST
[ Parent ]
you've obviously never shared a flight with an obese neighbour, complete with supersize passive farting...

~"When an inner situation is not made conscious, it appears outside as fate." Karl Jung~
by melo (melometa4(at)gmail.com) on Thu Jul 9th, 2009 at 05:16:43 PM EST
[ Parent ]
I'd suggest the preposition "on" as in "out on the plain..." ;]
by de Gondi (publiobestia aaaatttthotmaildaughtusual) on Thu Jul 9th, 2009 at 01:15:35 PM EST
[ Parent ]
No, apparently it's ok to ask things of smokers, but not anyone who is overweight.  It's ok to lecture people who are too thin about ruining their health and having perverse priorities, but not people who are too fat.  And I'm not talking about anyone who is less than ideal.  I'm not talking about making unrealistic demands on people.  No, question people who make the personal choice to spend of hours in front of the tv mindlessly eating crap, and you are discriminating against them.  I've no doubt they really are discriminated against, by prospective employers, etc.  But asking people to accept responsibility for the consequences of their actions?  That's not discrimination.  I make the personal choice to smoke occasionally.  As a result, I'm singled out for tax, I'm banned from entering anywhere but my home while doing it, and scowled at by passersby.  And I'm ok with that.  But if it were a bag of Cheetos in my hand and not a cigarette, I'd be off scott free.  I'd get two seats for the price of one.

wtf?

"Pretending that you already know the answer when you don't is not actually very helpful." ~Migeru.

by poemless on Thu Jul 9th, 2009 at 01:34:50 PM EST
[ Parent ]
I'm not bitter or anything. :)  Seriously, I've gained a good 5 lbs since the smoking ban took effect.  


"Pretending that you already know the answer when you don't is not actually very helpful." ~Migeru.
by poemless on Thu Jul 9th, 2009 at 01:37:08 PM EST
[ Parent ]
good five pounds? is it only the bad ten after that that you'd have to worry about? ;)

Any idiot can face a crisis - it's day to day living that wears you out.
by ceebs (ceebs (at) eurotrib (dot) com) on Thu Jul 9th, 2009 at 06:58:41 PM EST
[ Parent ]
Actually, I saw the dr last night, and science refuted my suspicion.  So make that an imaginary 5 lbs.

"Pretending that you already know the answer when you don't is not actually very helpful." ~Migeru.
by poemless on Fri Jul 10th, 2009 at 04:13:03 PM EST
[ Parent ]
There are cheaper ways to get weighed ;-)

You can't be me, I'm taken
by Sven Triloqvist on Fri Jul 10th, 2009 at 04:26:10 PM EST
[ Parent ]
LOL.  But not cheaper ways to get drugs, sadly.

"Pretending that you already know the answer when you don't is not actually very helpful." ~Migeru.
by poemless on Fri Jul 10th, 2009 at 04:27:47 PM EST
[ Parent ]


You can't be me, I'm taken
by Sven Triloqvist on Fri Jul 10th, 2009 at 04:36:14 PM EST
[ Parent ]
Nope. They say both diets in the experiment were healthy, the only difference being calorie intake.
by afew (afew(a in a circle)eurotrib_dot_com) on Thu Jul 9th, 2009 at 01:05:24 PM EST
[ Parent ]
this is nothing new - the theory that a low-calorie diet slows aging has been out there for quite a while. It looks like many of the people, like the Hunza, who used to become very old, had low-calorie diets.

And I think there have even been studies on  humans too, here just an example.

Low-Calorie Diet May Lead to Longer Life - New York Times

A low-calorie diet, even in people who are not obese, can lead to changes in metabolism and body chemistry that have been linked to better health and longer life, researchers are reporting.

The findings lend support to the theory that eating less, long known to prolong life in rats and mice, may do the same for people, by preventing heart disease, cancer, diabetes and other diseases, and by slowing aging.

The notion that going hungry could be the fountain of youth has captivated scientists and the public. Calorie restriction, the scientific name for a regimen high in nutrients but low in calories, is the subject of intense research, and some people have already begun trying it on their own.

There is a Calorie Restriction Society with members all over the world, and its president, Brian M. Delaney, estimates that the people experimenting on themselves number in the thousands.

by Fran (fran at eurotrib dot com) on Thu Jul 9th, 2009 at 01:03:48 PM EST
[ Parent ]
in some of the first health food shops in london, mid sixties, you could buy little dried hunza apricots, reputedly high in natural silver. they were unbelievably delicious, we used to crack open the seed and eat the kernel, for the laetrile.

i got curious about the hunzas, and learned they would happily walk every morning 5 miles to their fields and work there all day.

tough people, serious survivors.

~"When an inner situation is not made conscious, it appears outside as fate." Karl Jung~

by melo (melometa4(at)gmail.com) on Thu Jul 9th, 2009 at 05:21:28 PM EST
[ Parent ]
i eat less in a week now than i ate in three days growing up, and am much healthier for it.

the reasons it's so un-PC to criticise fatties is that they just eat more if you do.

besides, the problems people carry around that you can't see are much worse than the ones you can.

a government that cared about its people would ban junk food, for its effects on future generations, and the gene pool in general, as well as the horrendous environmental degradation it causes.

~"When an inner situation is not made conscious, it appears outside as fate." Karl Jung~

by melo (melometa4(at)gmail.com) on Thu Jul 9th, 2009 at 05:28:39 PM EST
[ Parent ]
i heard also a possible apocryphal story that prisoners in the concentration camps had no tooth decay, and that the reduced diets and greater reliance on wholegrains during the war led to much less sickness, that then returned to 'normal' afterwards...

~"When an inner situation is not made conscious, it appears outside as fate." Karl Jung~
by melo (melometa4(at)gmail.com) on Fri Jul 10th, 2009 at 03:30:44 PM EST
[ Parent ]
I haven't heard about the concentration camps, but read about various reports of people being healthier during war time, because they ate reduced calories and fat.
by Fran (fran at eurotrib dot com) on Fri Jul 10th, 2009 at 03:33:50 PM EST
[ Parent ]
And now that I think about it, that is amazing as during the war people must have been under tremendous stress and despite of that they seem to have been healthier.
by Fran (fran at eurotrib dot com) on Fri Jul 10th, 2009 at 03:37:15 PM EST
[ Parent ]
Well, I guess it all depends on the war and the camp.  I've heard stories that people starved to death in places like Auschwitz and Leningrad.  Like, A LOT of people.  Apparently lack of food can cause death in some people...

Now, let us please return to our sanity.  Thanks.

"Pretending that you already know the answer when you don't is not actually very helpful." ~Migeru.

by poemless on Fri Jul 10th, 2009 at 03:43:33 PM EST
[ Parent ]
point taken poemless, it's too easy to lose perspective sometimes.

what is amazing is how many people didn't starve to death, considering the conditions. the ability of the human body to stay alive notwithstanding the cruelty, with no reserves, negligable nutrition, and bitter cold beggars belief.

the fact that they had less tooth decay is relatively trivial, yet curious just the same...  

~"When an inner situation is not made conscious, it appears outside as fate." Karl Jung~

by melo (melometa4(at)gmail.com) on Sat Jul 11th, 2009 at 12:54:42 AM EST
[ Parent ]

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