Real Estate: as for every country, location is the main factor. The trendiest (and most expensive) communes of the Brussels region are Uccle, Woluwé-St-Pierre, Woluwé-St-Lambert and part of Ixelles. Typical price for a ready to move in house start at €500k. Auderghem and Boisfort are also nice to live in and a bit cheaper (350k+). In any other nice neighbourhood, a house will cost at least 250k. Two-bedrooms apartments start at around 150k. If your are ready to drive, there are also nice locations just outside Brussels (5-20km).

Transportation: public transports (3 metro lines + network of trams and buses) cover virtually every neighbourhoods in Brussels. Traffic is dense all day long , as in every European capital cities. It takes me at least one hour to reach my workplace in the centre of Brussels (26km journey).

Lifestyle: Brussels in probably the most international city in Europe (with London perhaps). However it is a small city (~1m inhabitants) and the number of events is lower than in the larger European capital cities like Paris or London. Activities and locations are dispersed across the city, there is no real entertainment area. Therefore you may need to make a few friends to introduce you to the good places.

Health care: generally excellent and cheap (we are a socialist country with universal health care coverage).

Food: very good with a lot of choice in meat, fish, vegetables and fruits in supermarkets. Although the sugar content in prepared food tend to increase, it is still way lower than in the US. Food is however more expensive than in the US. Very large and diversified choice of restaurants.

Work: be aware that as a non-EU national, you will need a work permit.