My concern is the popularization of metaphysical discussion. For example, there's a movie "What the Bleep Do We Know?" which makes some interesting points, but to do so it takes a mangled and simplified version of quantum mechanics and applies it to daily life.

It seems to me that the way to look at it is that the universe is a lot more complicated than we have noticed, and that it's likely that physics will advance as much in the next 100 years as it has in the last 103 (to include 1905 in the range) years. But such advances have nothing to do with religion or metaphysics, but with experimental evidence and hard math problems.