That depends how it's done. The companies offering statistical analysis assume you're using an off-the-shelf app. All they do is buy an app, run some tests, and create a profile.

But all that says is that most commercial steganography apps aren't all that good.

In the limit, good steganography is indistinguishable from compression artefacts and random noise. And if the bit rate is low enough and somewhat randomised, it becomes even harder to be confident about getting a clean positive.

There are also things like this.