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WHO: Ebola Can 'Transmit Freely' in DR Congo, Death Toll Hits 41
vaccination trial: mAb114
The outbreak in North Kivu's Beni region, which shares borders with Uganda and Rwanda, was declared a week after the WHO and the Kinshasa government hailed the end of an Ebola flare-up in northwestern Equateur province, which killed 33 people.
therapeutic trial: rVSV-ZEBOV
The latest outbreak, which now counts 57 probable and confirmed cases of the deadly virus, is the country's 10th since 1976 when the disease was first identified in the DRC near the Ebola River.
In a bid to halt the virus's lethal advance, DRC health authorities said Tuesday that doctors in Beni had begun using a prototype drug called mAb114 to treat patients.

The treatment is "the first therapeutic drug against the virus to be used in an active Ebola epidemic in the DRC," the health ministry's directorate for disease control said. Developed in the United States, the prototype drug is a so-called single monoclonal antibody -- a protein that binds on to a specific target of the virus and triggers the body's immune system to destroy the invader.

In May, the U.S. National Institute of Allergy and Infectious Diseases (NIAID) said it was carrying out the first human trials of mAb114 to test it for safety and tolerance.
Use of the experimental treatment in the field comes on the heels of deployment of an unlicensed vaccine in the earlier Ebola outbreak in the DRC this year. The decision to use the vaccine, called rVSV-ZEBOV, came after trials during the 2013-2015 pandemic in West Africa showed it to be safe and effective, the WHO says.

The vaccine played a significant role in halting Ebola's spread in Equateur province, and should also be useful in fighting the new outbreak. Targeted vaccination, aimed primarily at front-line health workers, began last week, and so far 216 people have received a jab.

Congo Ebola outbreak poses high regional risk, says WHO

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no cases having been reported for 45 days, 31 July
living lab, 12 May

Diversity is the key to economic and political evolution.

by Cat on Sat Aug 18th, 2018 at 08:43:19 PM EST
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