Welcome to European Tribune. It's gone a bit quiet around here these days, but it's still going.
One figure that has puzzled me since MSM first publicized it is, US influenza CFR is 0.1%. This figure is patently false. My question therefore was terms of the expression which produced it.

I suspected the error is the selected value of the denominator. I have shown here that the estimated frequency produced by CDC FluView modeling derives from deaths/hospitalization--ergo diagnosed, or "confirmed", cases, given numerous limitations in data collection, admitted by CDC.

Indeed, in review of numerous, spurious expositions published by innerboob amateur exposition, TOTAL POPULATION SIZE is the choice CFR denominator. This is stupidity beyond the pale of rudimentary principles of statistical description. And a problem in itself that cannot be remedied by quantities of money or PPE hastily delivered to everyone on the planet.

by Cat on Mon Mar 23rd, 2020 at 04:22:16 PM EST
Since Little Ronnie RayGuns started it Republicans have steadily chipped away at federal and state funding for Public Health.  Can't do data gathering and analysis if the people aren't there.

She believed in nothing; only her skepticism kept her from being an atheist. -- Jean-Paul Sartre
by ATinNM on Mon Mar 23rd, 2020 at 08:01:09 PM EST
[ Parent ]
There's huge confusion between CFR, Infection Fatality Rate, and Population Mortality.

CFR - deaths/known cases
IFR - deaths/estimated infections
PM - deaths as an absolute percentage of the population

You can't estimate the IFR accurately without statistically significant random population sampling. No country has done this, although Germany may have come closest. (Korea's sampling was skewed by explicit tracking of one subgroup.)

All of the above depend on the quality and availability of health care. There's no formal measure for Base Mortality, which is what you'd get if you exposed a large population and didn't provide any health care at all. That would be a population worst case, and for obvious reasons no one does this - although in fact it would still depend on basic health, social customs, and so on.

Allowing for 80% infection, which is an epidemiological worst case (likely true in the UK, not so much in countries with good early lockdown, plentiful testing, and case tracking) according to one estimate the likely population mortality will be around 0.15%.

Case Fatality Rates

Although the horror stories are getting the most attention, the reality is that around 70% of cases are either asymptomatic or mild.

But the others are bad news, because the remaining numbers will still overwhelm most health care systems - even the well prepared ones. And with asymptomatic transmission, the total number of infections will be higher than it would have been otherwise.

Putting all of that together with some guessing, the final death toll in the UK will likely be in the low six figures, or high five figures if the country is very lucky.

That's better than seven figure estimates you get by naively applying CFR to the entire population. But it's still going to be a life-changing outbreak for a lot of people, one way or another.

by ThatBritGuy (thatbritguy (at) googlemail.com) on Tue Mar 24th, 2020 at 01:57:49 PM EST
[ Parent ]
France was ready to shut border had UK not toughened coronavirus measures
PARIS -- French President Emmanuel Macron told British Prime Minister Boris Johnson on Friday that he would close the border if the U.K. did not take more restrictive measures to contain the coronavirus.

"We had prepared the closure of our border and told Prime Minister Johnson we would implement it that day if there was no evolution [of British measures]," a senior French official familiar with the conversation told POLITICO.

French paper Libération reported Saturday evening that Macron had "threatened" Johnson. The French official said that was "too strong a word" to describe the call.

Continental blockade barely averted.

by Bernard (bernard) on Tue Mar 24th, 2020 at 08:57:15 PM EST
[ Parent ]
Entente cordiale on full display.

'The history of public debt is full of irony. It rarely follows our ideas of order and justice.' Thomas Piketty
by melo (melometa4(at)gmail.com) on Sat Mar 28th, 2020 at 02:35:00 AM EST
[ Parent ]
I'll just leave this here for posterity, when the fingers quit wagging. Central limit etc etc

CDC | How CDC estimates Influenza-Associated Deaths in the U.S.

Laboratory-confirmed influenza-associated hospitalization rates are obtained from the Influenza Hospitalization Surveillance Network (FluSurv-NET), a collaboration between CDC, the Emerging Infections Program Network, and selected state and local health departments in 13 geographically distributed areas in the United States that conduct population-based surveillance. The network includes hospitals that serve roughly 9% of the U.S. population. The reported numbers of hospitalizations are used to calculate hospitalization rates and the rates are adjusted to correct for under-detection of influenza.  This adjustment is done by using the percent of persons hospitalized with respiratory illness who were tested for influenza and the average sensitivity of influenza tests used in the participating FluSurv-NET hospitals. The data on influenza testing can lag up to two years after the end of the season, so for more recent seasons, testing data from prior seasons is used (1).
Some people with influenza will seek medical care, while others will not. CDC estimates the number of people who sought medical care for influenza using data from the 2010 Behavioral Risk Factor Surveillance Survey, which asked people whether they did or did not seek medical care for an influenza-like illness in the prior influenza season (6).
The methods to estimate the annual number of influenza-associated deaths  have been described in detail elsewhere (1-2). The model uses a ratio of deaths-to-hospitalizations in order to estimate the total influenza-associated deaths from the estimated number of influenza-associated hospitalizations.
beside me da's urn, etched "failure to thrive"
Doctors And Nurses Say More People Are Dying Of COVID-19 In The US Than We Know
In the US, state and county authorities are responsible for collecting data on cases of [INSERT DISEASE], and deaths. The data is then reported to the Centers for Disease Control and Prevention.
by Cat on Sat Mar 28th, 2020 at 02:55:59 AM EST
[ Parent ]
Propounding categorical error and propaganda.

In most cases, I think, medical pros are trained to respond to hearts and minds of the living with a visceral, idiomatic explanation of death at the moment of death--whether or not its circumstance is "violent". However, additional responsibilities for and discrete knowledge of death's process also burden the medical pro. (eg. I had a strangely satisfactory exchange with the resident neurologist on evolving locutions for "brain death," while my ma lay dead and intubated.)

Final value assignment--industrial purpose for quantification--necessarily subordinates pathological minutia normally dismissed by the bereaved: proximal (pneumonia, myocardial infarction, etc) and distal (COVID-19, emphysema, etc) and comorbid disease(s)(diabetes, TB, etc) and pathogen (SARS-CoV-2, Staphylococcus, etc) and medical error or fraud.
Sorting Things Out, Classification and Its Consequences + diverse "bioethical" tracts in consideration of disparate bodies of information operating on perceptions of competence

by Cat on Sat Mar 28th, 2020 at 02:05:01 PM EST
[ Parent ]
The Data Whisperer
She has a way of spelling out the implications of the virus to Americans in personal terms while offering reassurances that the administration is approaching the pandemic with a data-driven mindset.
"knowledge base," sociolect, "experience-based" creditial. ahem.
Others worry that Birx, who stepped away from her job as the U.S. global AIDS coordinator to help lead the White House coronavirus response, may be offering Trump cover to follow some of his worst instincts as he considers whether to have people packing the pews by Easter Sunday.
< wipes tears >
by Cat on Sat Mar 28th, 2020 at 04:35:18 PM EST
[ Parent ]

Based on original flu modeling report from Imperial College in London with faulty assumptions.

'Sapere aude'

by Oui (Oui) on Sat Mar 28th, 2020 at 05:27:39 PM EST
[ Parent ]
by Cat on Sat Mar 28th, 2020 at 06:04:55 PM EST
[ Parent ]
Probably true at this stage, given they have wasted so much time when they could have been working on reducing that number!

Index of Frank's Diaries
by Frank Schnittger (mail Frankschnittger at hot male dotty communists) on Sat Mar 28th, 2020 at 07:19:21 PM EST
[ Parent ]


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