Latest Data Omicron Variant | 155 comments (155 topical, editorial, 0 hidden)

Learning from Covid, researchers prep universal vaccine for next coronavirus outbreak, 2021

In November, the Walter Reed [Army Institute of Research] vaccine -- which would provide immunity against several different coronaviruses -- completed phase 1 human trials [n=29 after exclusions], marking an important step forward. Unlike the mRNA vaccines developed at warp speed to combat Covid-19, universal coronavirus vaccines remain several years away from distribution.

Fauci pushes for universal coronavirus vaccine, 2021

reference
C-SPAN | Universal Flu Vaccine Milkin Institute panel, 2019
feat. Fauci
Warren offers infectious-disease plan amid China outbreak 2020
"including a universal immunization against the flu ... to increase NIH funding by $100 billion"

archived living lab Thu Jan 30th, 2020

by Cat on Fri Dec 17th, 2021 at 11:31:17 PM EST

Re: Latest USAMRIID ebola marketing (none / 1)

Congo declares end [again] to latest Ebola outbreak in the east

Research has shown that the first case from the latest outbreak "likely represented a new flare-up of the 2018-2020 Ebola outbreak due persistence of the virus in the community," WHO said Thursday.
Scientists have previously documented Ebola survivors who inadvertently [?!] infected others long after they had recovered. For example, health officials have warned that the virus can persist in male survivors' semen for more than a year.
[...]
While the 2018-2020 pandemic [sic] marked the first time that vaccines could be given to those at risk, insecurity in rural areas prevented health workers from safely accessing many.

Not contained, new cases: three questions on vaccines and the Ebola outbreak in DRC, 2019

Right now, "ring" vaccination is being used. This entails vaccinating anyone who's been in contact with someone infected with Ebola, as well as all of their contacts. The reasoning behind the method isn't bad per se. But implementing it is time-consuming and challenging (problems with identifying each and every person's individual contacts) and it's not adapted to the insecurity affecting North Kivu.

archived living lab
Sat May 12th, 2018 vaccines,
Tue Jun 4th, 2019 Merk,
Sat Aug 18th, 2018 more vaccines,
Fri Mar 13th, 2020 ring vaccination

by Cat on Sat Dec 18th, 2021 at 12:26:20 AM EST
[ Parent ]

Re: Latest USAMRIID Data UPDATE! (none / 0)

US Army Wraps Preclinical Trials on COVID-19 Vaccine Designed to Combat Variety of Variants

While the SpFN has yet to be tested on the omicron variant, "testing against the variants is ongoing in a ["]neutralization["] assay [FKA serological assay AKA antibody test] in the laboratory [in vitro]," the facility noted. The WRAIR went on to claim that facility scientists "remain encouraged" by early data from preclinical trials, which were published on December 16 in Science Translational Medicine, an interdisciplinary medical journal.

means, motive, opportunity

Researchers are now analyzing data from Phase One of human trials, but no timeline was provided. The WRAIR's protein subunit nanoparticle [FKA CRISPR substitution] vaccine works by presenting a fragment of the SARS-CoV-2 virus to one's immune system to elicit a broad, protective response. The SpFNincludes ALFQ, a vaccine adjuvant that is part of the Army Liposome Formulation (ALF) family[
[..]
According to the facility, the vaccine could potentially be useful on a global scale, as it remains stable at a wide range of temperatures, unlike the Pfizer-BioNTech and Moderna-developed vaccines, which require refrigeration.
[...]
"We need to evaluate it in the real-world setting and try to understand how does the vaccine perform in much larger numbers of individuals who have already been vaccinated with something else initially [...] or already been sick," [Dr. Kayvon Modjarrad] told the outlet in an exclusive interview.