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APsplainin Omicron-stricken South Africa may be glimpse into the future past
New COVID-19 cases in South Africa have burgeoned from about 200 a day in mid-November to more than 16,000 on Friday. Omicron was detected over a week ago in the country's most populous province, Gauteng, and has since spread to all eight other provinces, Health Minister Joe Phaahla said.

Even with the rapid increase, infections are still below the 25,000 new daily cases that South Africa reported in the previous surge, in June and July.
Genomic data for samples collected in May 2021 are available for all 9 provinces, and 70% of 739 genomes from May were the Beta variant (Fig 2). The Alpha, Delta and Eta variants account for 6%, 14% and 1% of the May genomes. For June 2021, genomic data are available for 5 provinces, with 603 sequences available on GISAID. Genomes sequenced (n=603) from samples collected in June 2021 shows 36% Beta and 49% Delta variant frequency with the Alpha variant accounting for 6% (Fig 2).
"What we must re-emphasize is that while our scientists and those in Botswana were the first discover and report on the variant, no one knows where it originated," Phaahla said.
SA | National Institute for Communicable Diseases
by Cat on Fri Dec 3rd, 2021 at 07:45:46 PM EST
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NO EVIDENCE THAT 501.V2 VARIANT IS MORE DANGEROUS THAN UK VARIANT, 24 Dec 2020
We have, however, noted the statement delivered yesterday by the Secretary for Health in the United Kingdom, Matt Hancock, and must register our concern that some of his utterances have created a perception that the variant in SA has been a major factor in the second wave in UK. This is not correct. There is evidence that the UK variant developed earlier than the South African variant. To give some historical context, on 14 December, the UK reported to the WHO that a variant had been identified and traced back to 20 September 2020 in Kent, South East England- approximately a month be- fore the South African variant appears to have developed. This variant has a mutation occurring at a site common with the South African variant (the 501), although they are two completely independent lineages. The UK variant is thought to be driving the second wave that the UK are experiencing currently.
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Dr. Zwelini Mkhize, Minister of Health
by Cat on Fri Dec 3rd, 2021 at 07:58:35 PM EST
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by Cat on Fri Dec 3rd, 2021 at 08:14:35 PM EST
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Study can't confirm lab results for many cancer experiments
"The truth is we fool ourselves. Most of what we claim is novel or significant is no such thing," said Dr. Vinay Prasad, a cancer doctor and researcher at the University of California, San Francisco, who was not involved in the project.
where the profit principle collides with genetic, spontaneous, or acquired neutropenia afflicting "the most" vulnerable "immunosuppressed/immunocompromised" consumer-patients on the planet and

SAR-CoV-2


VOI, VOC, VOHC as well as bacterial, fungal, and parasitic organisms for which either no specific prophylactic, therapeutic agent, or cure is common knowledge  
by Cat on Tue Dec 7th, 2021 at 06:13:37 PM EST
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NICD | COVID-19 VACCINE BREAKTHROUGH CASES FREQUENTLY ASKED QUESTIONS
WHY ARE SO MANY PEOPLE GETTING SICK OR TESTING POSITIVE AFTER VACCINATION, AND HOW ARE WE KEEPING TRACK OF SUCH CASES?
The vaccines are not 100% effective, so we would expect breakthrough infections. The majority of these will be mild. For the Sisonke study, so far 94% of breakthroughs were mild, 4% moderate and 2% severe.

When the rate of infection is very high there will be more breakthrough infections. Once population immunity levels rise with increased vaccination, there will be less transmission of the virus and fewer breakthrough infections. Any events that happen after vaccination must be reported so that these can be investigated. There is a Medsafety app and details can be found by visiting medsafety.sahpra.org.za.

South African Medical Research Council: SAMRC | Report on Weekly Deaths in South Africa, 29 Dec 2019 - 27 Nov 2021, illustrated
One approach to aid understanding of the emerging COVID-19 mortality is to compare the estimated weekly excess deaths with the number of COVID-19 deaths reported by the Minister of Health as shown in the figure below. This comparison is hampered to some degree by the fact that the excess deaths are classified by week in which the death occurred; the reported COVID-19 deaths are classified by date the numbers are reported to the Department. If all excess natural deaths were due to COVID-19, and all COVID-19 deaths were perfectly identified and reported, the two series would be identical. The number of estimated excess deaths has begun to decrease, consistent with the trend in the number of confirmed COVID-19 deaths. Although more data are needed on the underlying causes of death, this observation is strongly supportive that a significant proportion of the current excess mortality being observed in South Africa is likely to be attributable to COVID-19.
by Cat on Fri Dec 3rd, 2021 at 08:10:20 PM EST
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