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Yes, they're allowing a 12 week gap between shots, when the trial data is based on a 3-4 week gap. I actually think there is a legitimate epidemiological case for this, as studies indicate even the first dose of the Pfizer vaccine offers a very high level of protection, whereas the second dose only boosts this by 10% or so.

If that is the case, and you get one person 85% protected with 1 shot, it may make sense to delay the second shot and give it as a first shot to someone else who will be 85% protected rather than boosting the first person by only another 10%.

From an individual point of view, you want to get max protection asap, but from a herd immunity perspective, you get more bang for you buck by spreading the doses more.

Of course medical opinion is divided on this and we won't be sure what is the most effective strategy for some time yet. But to me it seems getting as many people 85% protected as possible ASAP is a better strategy to avoid further spread.

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by Frank Schnittger (mail Frankschnittger at hot male dotty communists) on Thu Apr 1st, 2021 at 07:44:23 PM EST
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