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With Covid-19 running rampant at 50k+ cases a day:

[UK] ... Ministers argue that the vaccination programme, under which 87.8% of the adult population has had one vaccine and 67.8% have been double vaccinated, has largely broken the link between cases and mortality. [1]

But what hasn't been broken is the link between cases and long term sequelae.  

The acute clinical manifestations of COVID-19 have been well characterized but the post-acute sequelae of this disease have not been comprehensively described. Here we use the national healthcare databases of the US Department of Veterans Affairs to systematically and comprehensively identify 6-month incident sequelae--including diagnoses, medication use and laboratory abnormalities--in patients with COVID-19 who survived for at least 30 days after diagnosis. We show that beyond the first 30 days of illness, people with COVID-19 exhibit a higher risk of death and use of health resources. Our high-dimensional approach identifies incident sequelae in the respiratory system, as well as several other sequelae that include nervous system and neurocognitive disorders, mental health disorders, metabolic disorders, cardiovascular disorders, gastrointestinal disorders, malaise, fatigue, musculoskeletal pain and anaemia. We show increased incident use of several therapeutic agents--including pain medications (opioids and non-opioids) as well as antidepressant, anxiolytic, antihypertensive and oral hypoglycaemic agents--as well as evidence of laboratory abnormalities in several organ systems. Our analysis of an array of prespecified outcomes reveals a risk gradient that increases according to the severity of the acute COVID-19 infection (that is, whether patients were not hospitalized, hospitalized or admitted to intensive care). Our findings show that a substantial burden of health loss that spans pulmonary and several extrapulmonary organ systems is experienced by patients who survive after the acute phase of COVID-19. These results will help to inform health system planning and the development of multidisciplinary care strategies to reduce chronic health loss among individuals with COVID-19. [2]

[emphasis added]

The UK is hopeless.  (So is the US for that matter, a different discussion.)

Unless the imposes strict quarantine measures on the UK (and US) NOW to prevent avoidable Covid-19 cases on the continent.  The Northern Ireland/UK border is of particular concern.  If Covid carriers are not stopped at ports of entry they will infect the island with the Delta variant (B.1.617.2.) If Unionists and the Brits aren't willing to take proper care the the question the Republic needs to answer is, "how many Irish do they want to kill or have Covid sequelae to keep the Northern Ireland border open?"

[1]  UK PM Johnson reverses plan to skip quarantine after COVID exposure

[2]  High-dimensional characterization of post-acute sequelae of COVID-19

She believed in nothing; only her skepticism kept her from being an atheist. -- Jean-Paul Sartre

by ATinNM on Sun Jul 18th, 2021 at 03:14:17 PM EST

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