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I would be surprised if that did not also extend to likelihood of transmission.

The only metric for viral communicability was/is R(0), a function predicting CASE VOLUME over time and predicated by average P2P contact frequency, promulgated by epidemiologists, the Big Data specialists--not biologists, virologists, or clinicians.

According to my knowledge and belief, general interest in "pre-omicron" variants, circulating the world, has been limited to exactly two (2) by MSM press. However, geneticist had reported variable trajectories in Phylogenetic network analysis of SARS-CoV-2 genomes recovered from serum samples as early as 15 April, 2020.

The network faithfully traces routes of infections for documented coronavirus disease 2019 (COVID-19) cases, indicating that phylogenetic networks can likewise be successfully used to help trace undocumented COVID-19 infection sources, which can then be quarantined to prevent recurrent spread of the disease worldwide.

In the R&D contest for vaccine EUA (Dec 2020), the latter began disseminating structural analyses of SAR-CoV-2 "Wuhan strain" AKA "pre-Alpha" and Alpha (GB "variant of interest", Victoria) which established measures of candidates' efficacy purporting either to retard cellular replication of that specific viral RNA or COVID-19 disease morbidity and mortality rate, regardless of inevitable SARS-CoV-2 genomic variation.

The presumption that virus mutations are "stable" or can be mechanically controlled by simultaneously inoculating every one on the planet with one or two obsolete mRNA remedies, formulated one year ago for one genome sequence, is irrational. Yet it lingers in the popular imagination of the power of R(0), mastery of intangible phenomena and P2P freedom from the "unvaccinated" whose contributions, even sacrifices, to scientific truth and biological diversity are not well-understood.

by Cat on Fri Jan 21st, 2022 at 04:40:23 PM EST
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