Welcome to European Tribune. It's gone a bit quiet around here these days, but it's still going.
yer boy Fauci speaking at the World Economic Forum's Davos Agenda online conference
"it is an open question whether it [SARS-CoV-2 omicron] will be the live virus vaccination that everyone is hoping for," according to CNBC.

"I would hope that that's the case. But that would only be the case if we don't get another variant that eludes the immune response of the prior variant," he added.

by Cat on Tue Jan 18th, 2022 at 01:27:17 AM EST
strikes again. I suppose the ideal scenario is a highly infective, low virulence variant which provides immunity to other more seriously virulent variants and effectively wipes them out.  This is (almost) what has happened in Ireland - a huge spike in cases, a big (but compared to Delta, a moderate) rise in hospitalisations, and very little impact on intensive care or ventilated case numbers and deaths.

New cases are now falling precipitously, despite a gradual loosening of lock down measures and a re-opening of schools after the holidays. With 90%+ double vaccination rates, including increasingly young children now and boosters plus a 22% of the population infected rate, its about time Herd immunity has kicked in.

That is not to say earlier strict lockdown measures were not necessary and effective. Ireland's death rate is abut half that of the UK despite an open land border with N. Ireland and a free travel area with Britain, and despite a more inclusive definition of what constitutes a "Covid death". (Early UK figures didn't include deaths outside hospitals and still count only cases with a positive test within 4 weeks of death and are about 30% lower than the number of cases which mentioned Covid as a contributory factor on the death cert).

Index of Frank's Diaries

by Frank Schnittger (mail Frankschnittger at hot male dotty communists) on Tue Jan 18th, 2022 at 10:42:18 AM EST
[ Parent ]
SARS-CoV-2 variants are still infecting vaccinated* and unvaccinated people: "Confirmed and probable" CASE VOLUME alone has defined the success (failure) of pharmaceutical (P) and non-pharmaceutical (NP) "interventions" ordered by governments ostensibly to eliminate all instances of all variants of SARS-COV-2 ("coronavirus") circulating human and non-human populations. Which is ridiculous. No manufacturer ever claimed in EUA apps to eliminate (innoculate, immunize, or, now, "neutralize" VOCs), merely mediate risks of "severe illness or death" indicated by serum ANTIBODIES.

BUT estimates and counts (if any) are not 1:1 case per person. Just so, double- and triple-count DOSAGE exaggerate the cumulative number of vaccinated persons. IF you can find a "dashboard" or peer-reviewed (tiny) sample case studies that differentiate subject "immunity" by multiple infection or multiple dosage per person, post it. Here NY State Health Department methodological notes typify statistical error and common institutional ignorance, otherwise reserved for primitive Third World countries and commies.

What has appeared in HOSPITALIZATION and DEATHS reporting over the prior 8 months is, those numbers are not increasing at the same rate as case volume. It is a mistake to presume that vaccination alone is a limiting factor on case volume--despite relentless pop fiction disseminated by MSM "experts" who routinely exclude ALL-CAUSES in reporting either metric in order to tie vaccination uptake to "herd immunity". Which is ridiculous. How could you (pl.) forget that members of this board interrogated rampant COMORBID diseases ("pre-existing-," "underlying-" or "immune-compromised" conditions), relevant and irrelevant DEMOGRAPHIC traits, and MEDICAL ESTABLISHMENTS' services and equipment in the first 2 years of commonsensical multi-factor analysis of mortality rates? How could you dismiss persistent "with?" or "from?" causal controversy in custodial reporting? How have some become enthralled with the poetry of inert RNA transformed into a winged parasitic organism capable of spontaneous REPRODUCTION and PLANNING its "escapes" and "survival" by "selecting" anti-vaxxers?

CDC measles, PHIL ID #21074, CDC influenza A virus, CDC coronavirus, PHIL ID #23312, CDC coronavirus, PHIL ID #23312, USAToday front page, 01/11/22

"Experts" have admitted "herd immunity" is a canard--a ploy to establish NEW! product lines of maintenance drugs and supply of human "hosts" for experimentation. It's time to admit that, to interrogate the urgency and end-point of you consenting to indiscriminate, novel "interventions" whose actual recombinant and chemical properties as well clinical benefit are alternately unknown or little understood.

Morens, Taubenberger, Fauci, "Universal Coronavirus Vaccines -- An Urgent Need", NEJM. 15 Dec 2021

To gain insights into natural history and pathogenesis, it will be important to study the coronaviruses that were[?] probably once pandemic [WTAF] but have now[?!] become endemic. These four viruses ― the betacoronaviruses OC43 and HKU1 and the alphacoronaviruses 229E and NL63 ― cause mostly mild upper respiratory infections and can be studied in laboratory animals and in humans to characterize their epidemiology, cell tropism, elicited immune responses, cross-reactive and cross-protective epitopes, and the mechanisms by which they ["]survive["] and evolve in the face of high population immunity[?!]. Ethical human challenge studies4 can be conducted using modern genomic, transcriptomic, and immunologic tools.
by Cat on Tue Jan 18th, 2022 at 04:56:49 PM EST
[ Parent ]
Although clinical studies of vaccine efficacy will ultimately be needed
none exist
we must also begin now to investigate correlates of human immunity after both natural SARS-CoV-2 infection and vaccination, including by evaluating the durability of responses and their localization (mucosal and systemic).
false dichotomy
Human challenge [!] studies with the human "cold virus" coronaviruses (e.g., OC43) will probably be important.
ya think?
by Cat on Tue Jan 18th, 2022 at 05:58:46 PM EST
[ Parent ]
Do multiple boosters 'exhaust' our immune responses?
Fourth doses of the COVID-19 vaccine don't appear to offer significant protection against catching omicron according to a preliminary study conducted in Israel, the first country to authorize a [first and] second booster for its general population.
These findings appear to confirm doubts expressed by the European Union's top drug regulator last week. Marco Cavaleri, the European Medicines Agency's head of vaccines strategy, said at a news briefing there's no data supporting the broad effectiveness of fourth boosters.
Researchers say that although it's true that there's no clinical data proving the effectiveness of multiple boosters, there's also no science to back up the idea that frequent boosters could cause "fatigue" in the population. That's because the research has never been attempted.
While T cell [B-cell?]exhaustion can be observed in cancer or HIV patients in response to some immune-based treatments, it's never been observed in humans in response to frequent COVID-19 vaccination. Obst said that although there's little clinical data behind it, Cavaleri's concern makes sense.
The COVID-19 vaccines have been held to an impossible standard, he said. When the phase three studies on the quality of the Moderna and Pfizer vaccines were presented in the US in December 2020, they showed claimed a 95% efficacy against mild [COVID-19] illness.
by Cat on Tue Jan 18th, 2022 at 07:03:58 PM EST
[ Parent ]
Thanks! This is restoring a bit of my trust in the EMA. I am afraid the guy should already look for his next job because I doubt his contract will be renewed, when time comes.
Isn't it obvious that people are a bit scared when they read (here: https:/www.ema.europa.eu/en/documents/product-information/covid-19-vaccine-janssen-epar-product-inf ormation_en.pdf): "The safety and efficacy of COVID-19 Vaccine Janssen in children and adolescents (less than 18 years
of age) have not yet been established. No data are available." or "Interaction with other medicinal products and other forms of interaction
No interaction studies have been performed. Concomitant administration of COVID-19 Vaccine
Janssen with other vaccines has not been studied." (the latest point is not true, the Philippines did... but it was 'government' funded apparently... not enough for JandJ aparently:
www.philstar.com/headlines/2022/01/10/2152809/dost-funded-covid-19-vaccine-mix-and-match-stu dy-underway)

In fact the other vaccines have also not been studied for interaction with other medicinal products. (Corminary aka Pfizer, https:www.ema.europa.eu/en/documents/product-information/comirnaty-epar-product-information_en.pdf )

But apparently we are expected to 'suspend judgment' and  stop reading miindications

Also, we are still using these under "conditional authorization"
/www.ema.europa.eu/en/human-regulatory/overview/public-health-threats/coronavirus-disease-cov id-19/treatments-vaccines/vaccines-covid-19/covid-19-vaccines-authorised

by Tom2 on Wed Jan 19th, 2022 at 12:28:47 PM EST
[ Parent ]
Pandemic deaths rise by 12% as cases soar
The body of this AFP database digest is increase of CASE VOLUME ranging -25% to +327%.

Who do you trust with "empirical evidence" and your very own health care?
What have you learned about pharmaceutical and non-pharmaceutical intervention and clinical remedies for COVID-19 infection?
Are you really going to base that decision on diverging statistical descriptions and florid headline news?
archived What this means, I believe ...
by Cat on Wed Jan 19th, 2022 at 02:23:41 PM EST
[ Parent ]
The rich world leading the race. What a complete 360° in comparison with the worldwide protests all around the pre-covid world against the destruction of the environment, junk food, pollution etc. Now you need a car to go anywhere without being asked (by anyone, the bus driver, the bar's waiter, the cinema cashier, the school teacher...) for your "health" ID. And be happy you have one! it means you are in a "protective" system (wonder where Medicare fits into that).
The American dream, a car for all.
by Tom2 on Wed Jan 19th, 2022 at 08:13:28 PM EST
[ Parent ]
POLITICO < CDC: Vaccinated Americans with a prior infection fared the best during Delta
The study did not explain why protection against reinfection and hospitalization grew among those individuals with a prior infection during Delta.

The study, published Wednesday, looked at four categories of people in New York and California -- individuals who were unvaccinated with and without a prior infection and vaccinated people with and without a prior infection.
Eli Rosenberg, deputy director for science at the New York State Department of Health who helped with the study, said "the totality of the evidence suggests ... that both vaccination and having survived Covid each provide protection against subsequent infection and hospitalization." "Either of those provides protection, and only one of those is the safe choice that we would recommend. And that's vaccination," he said.

REUTERS | Prior COVID infection more protective than vaccination during Delta surge -U.S. study
Protection against Delta was highest, however, among people who were both vaccinated and had survived a previous COVID infection, and lowest among those who had never been infected or vaccinated, the study found.
COVID-19 Cases and Hospitalizations by COVID-19 Vaccination Status and Previous COVID-19 Diagnosis -- California and New York, May-November 2021, Early Release / January 19, 2022 / 71

well, alrighty then
archivedSCOTUS oral argument, NFIB v. Dept. of Labor

JUSTICE SOTOMAYOR: Others, unvaccinated people at risk and people who are vaccinated. They may be at a lesser risk, but the grave risk remains to people of all ages and conditions that are unvaccinated.
MR. FLOWERS: Right, but -- but the problem is they've defined numerical probabilities that are equal to be grave in one case and not grave in the other, and that is the definition of irrational.
NY Health methodological notes
by Cat on Wed Jan 19th, 2022 at 08:40:09 PM EST
[ Parent ]
This is interesting that Ireland had the booster campaign under strict lockdown, same as UK vaccination campaign a year ago and actually what is recommended rather than mass vaccination in the midst of full circulation of the virus(es), as in most countries.
by Tom2 on Tue Jan 18th, 2022 at 09:21:49 PM EST
[ Parent ]


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