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How does what work? The gene is only claimed to pre-dispose a person to severe illness. As such genetic testing and future counter measures may help to reduce severe illness and death and reduce Cov-19 to the status of an endemic flu to be managed by more conventional measures. It doesn't really effect the current civil liberties argument addressed in the diary.

Index of Frank's Diaries
by Frank Schnittger (mail Frankschnittger at hot male dotty communists) on Mon Jan 17th, 2022 at 04:36:46 PM EST
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If at least one version of the gene is present in the chromosome [...]
This is so wrong, that I had to go and check the news from University of Bialystok site, too. And it's even there. Must be bad translation, or something. Because everyone has at least one version of the gene, most people have two.

Elsewhere they did say they identified a variant that doubles the risk of severe covid infection. As all this was announced in a press conference, not in a peer reviewed publication, we don't really know what methodology they used. If was "merely" an association analysis, they can well be way off, since it's basically just regression analysis done the wrong way. There's always a big chance that the "association" is just a statistical fluke due to the method doing it's best to find something.

The best would be for somebody to come up with a testable biochemical explanation why a certain variation of a certain gene raises the risk of severe infection. The we would, perhaps, learn how to mitigate it in all patients.

by pelgus on Mon Jan 17th, 2022 at 05:06:46 PM EST
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by Tom2 on Mon Jan 17th, 2022 at 09:39:22 PM EST
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Organic chemistry is hard work even with CRSPR equipment.
Biostatistical sampling errors are way more fun.
So is cherry-picking genes.

"Pool testing" state of the art UPDATE!
UK virus hunting labs seek to bolster global variant network

The laboratory is one example of how British scientists have industrialized the process of genomic sequencing during the pandemic, cutting the time and cost needed to generate a unique genetic fingerprint for each coronavirus case analyzed.
DNA collected from air could revolutionize the monitoring of biodiversity
"The non-invasive nature of this approach makes it particularly valuable for observing vulnerable or endangered species as well as those in hard-to-reach environments, such as caves and burrows. They do not have to be visible for us to know they are in the area if we can pick up traces of their DNA, literally out of thin air," Clare said.
archived Rein in the four horsemen of irreproducibility
by Cat on Mon Jan 17th, 2022 at 10:08:20 PM EST
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Now that we are all MGOs anything can happen, I guess. And for those who aren't they won't be allowed to move from their caves anymore. Arts and culture are under huge pressure without much help in sight unless they sell to a multinational.

Lifted from NC comments:
Denmark sitrep:

  • cases are remaining stable, but still mighty high (2k per 100k case rate)

  • the Danish SSI has successfully mixed the 95%+ omikron case data with the 5% delta data to get rid of the omikron being overrepresented in the double-vaccinated (being roughly 2x more likely than a completely unvaxxed to get omikron) and is full speed on everyone get boosters

  • both recovered & vaccinated EU QR-code coronapasses now expire at 5months (even though SSI data itself shows that reinfection risk after vax is 90% (10% protection) at 9 months and 20% (80% protection) for unvaccinated). Just yesterday 900k greenpasses (1/7th of the population) expired. 3 times weekly spending 30min in test queues or just get another jab.

  • one a personal note - going with the traditional Danish disease vector = Kindergarten, our little one brought omikron home & now the whole household is sick. Mostly just a shitty 24h of fever & headaches followed by mediocre enjoyment fatigue days, but all recovering. Even got to try out me horsey medication (didn't feel that I needed it, but just to squash tail risk).

  • due to the expiry of the needed QR greenpasses (if you work in ed or health), we have friends chasing sick people to get an infection `booster' - he's a Pharma PhD working on RNA and him & family has refused to take `experimental/ EUA products' all the way. Peverse health incentives.
by Tom2 on Mon Jan 17th, 2022 at 10:42:52 PM EST
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hmm, yes, well, conceptions of liberty--according to European intellectual history-- is rather fraught with exceptions, cautionary tales, and misapprehension of the exclusive "rights" and superseding "interests of" a state, typically expressed as the "consent of the governed" opposed to, ahem, abject tyranny.

I can't speak to any political culture, or folkways common to the peoples inhabiting Ireland, but you have offered much insight to historical struggles to differentiate authorities of church and state--most conspicuously proved pertinent by constitutional amendment re: abortion.

So, my immediate appreciation for your observations is that (i) indeed, the balance of private and public "goods" models ethical rather than reactionary discourse; and (ii) I do hope, publication of this letter stimulates your readers to examine their expectations and the very real limitations of modern medical arts--alone or in concert with bureaucratic police apparatus--in eliminating moral hazards every minute, every hour, every day.

by Cat on Mon Jan 17th, 2022 at 08:44:24 PM EST
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COVID: Germany sputters on vaccine mandate
Many opponents of such a policy cite a statute in Germany's constitution, the Basic Law: It mandates that the government must protect people's health and safety and prohibits the government from interfering with a person's right to make their own choices about what happens to their body.

The Infektionsschutzgesetz (infection protection law) allows state and federal governments to mandate immunization for at-risk parts of the population" against a "contagious disease that presents clinically severe outcomes and when its epidemical spread is expected."

A widespread vaccine mandate would have to walk the line between these two contradictory elements very carefully or risk being thrown out by the courts. This has been the case in the United States, where President Joe Biden's order that large companies mandate vaccines for workers was thrown out by the Supreme Court, citing arguments of government overreach.

by Cat on Mon Jan 17th, 2022 at 09:43:42 PM EST
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by Cat on Mon Jan 17th, 2022 at 09:53:59 PM EST
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Doctors in Germany are forbidden by law from providing information on abortion procedures

It took me 1 minute to find a list of doctors that perform abortions. Is that  possible in the US?

by gk (gk (gk quattro due due sette @gmail.com)) on Tue Jan 18th, 2022 at 12:04:13 AM EST
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One might imagine, no, given the EXPLOSION this year of concern for and litigation on behalf of poor menstruating persons of color fleeing undue burdens foisted on them by "deputies" of the several states ... and the SCOTUS scrutiny of "informational interest" of the states.

NIFLA v. Becerra 20 Mar 2018

The FACT Act requires clinics that primarily serve pregnant women to provide certain notices. Clinics that are licensed must notify women that California provides free or low-cost services, including abortions, and give them a phone number to call. Its stated purpose is to make sure that state residents know their rights and what health care services are available to them. Unlicensed clinics must notify women that California has not licensed the clinics to provide medical services. Its stated purpose is to ensure that pregnant women know when they are receiving health care from licensed professionals. Petitioners--two crisis pregnancy centers, one licensed and one unlicensed, and an organization of crisis pregnancy centers--filed suit. They alleged that both the licensed and the unlicensed notices abridge the freedom of speech protected by the First Amendment.
Even if the State had presented a non-hypothetical justification, the FACT Act unduly burdens protected speech. It imposes a government-scripted, speaker-based disclosure requirement that is wholly disconnected from the State's informational interest. It requires covered facilities to post California's precise notice, no matter what the facilities say on site or in their advertisements. And it covers a curiously narrow subset of speakers: those that primarily provide pregnancy-related services, but not those that provide, e.g., nonprescription birth control. Such speaker-based laws run the risk that "the State has left unburdened those speakers whose messages are in accord with its own views." For these reasons, the unlicensed notice does not satisfy Zauderer, assuming that standard applies. Pp. 17-20. 839 F. 3d 823, reversed and remanded.

THOMAS, J., delivered the opinion of the Court, in which ROBERTS, C. J., and KENNEDY, ALITO, and GORSUCH, JJ., joined. KENNEDY, J., filed a concurring opinion, in which ROBERTS, C. J., and ALITO and GORSUCH,JJ., joined. BREYER, J., filed dissenting opinion, in which GINSBURG, SOTOMAYOR, and KAGAN, JJ., joined.

archived Tue Jun 26th, 2018
by Cat on Tue Jan 18th, 2022 at 03:16:42 AM EST
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by Cat on Fri Jan 21st, 2022 at 06:15:26 PM EST
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