Welcome to European Tribune. It's gone a bit quiet around here these days, but it's still going.
Some might have dismissed this information last December. Many likely haven't seen the label on the bottle, and in any event the constituents of each mRNA patented vaccine (apart from "delivery platform") aren't public knowledge. Which isn't to suggest expert organic chem knowledge is required to understand prerequisite novelty in design to acquire a patent.
Where's muh patent waivers?
WHO makes interim recommendations for mixing and matching COVID-19 vaccines
EU agencies endorse mix-and-match of COVID-19 vaccines

Japan breaks ranks
LIVING OFF ebola marketing mix 'n' match UPDATE
How'd that work out?

by Cat on Wed Jan 19th, 2022 at 02:58:15 PM EST
[ Parent ]
A Simple Breakdown of the Ingredients in the COVID Vaccines

She believed in nothing; only her skepticism kept her from being an atheist. -- Jean-Paul Sartre
by ATinNM on Wed Jan 19th, 2022 at 04:32:26 PM EST
[ Parent ]
Indeed, that's the "delivery platform," or suspension, encapsulating the "the viral protein" (or synthetic RNA). The former is known to interested parties, the latter is not well reported.
After injection, the mRNA from the vaccine is released into the cytoplasm of the cells. Once the viral protein is made [HOW?] and on the surface of the cell, mRNA is broken down [metabolized?] and the body permanently gets rid of it[see? this is why ppl be searching for "black box warnings" and biochemical summaries exactly describing eg. waste product, bc EUA holders' reporting is faint], therefore making it impossible to change our DNA.
I must stress, I am not and have never suggested mRNA material alters cellular DNA. Rather like creation of "cancer cells", cellular DNA prescribes/transcribes mRNA transformation of normal surface structure ("binding domain") of human cells, mainly epithelial, which occur in form or another as tissue throughout the human body, into an unpredictable "pathway" of lymphatic responses to any and all antigens, including SARS-CoV-2. The mRNA mechanisms of action (MOA) said to "protect" cells is not well-understood.
by Cat on Wed Jan 19th, 2022 at 10:41:26 PM EST
[ Parent ]
Comirnaty contains nucleoside modified mRNA (modRNA) encapsulated in lipid nanoparticles that deliver the modRNA into host cells. The lipid nanoparticle formulation facilitates the delivery of the RNA into human cells.12 Once inside these cells, the modRNA is translated by host machinery to produce a modified SARS-CoV-2 spike (S) protein antigen, which is subsequently recognized by the host immune system. Comirnaty has been shown to elicit both neutralizing antibody and cellular immune responses to the S protein, which helps protect against subsequent SARS-CoV-2 infection

AbsorptionNot Available

Volume of distribution Not Available

Protein binding Not Available

Metabolism Not Available
Route of elimination Not Available

Half-life Not Available

Clearance Not Available

by Cat on Wed Jan 19th, 2022 at 11:04:11 PM EST
[ Parent ]
a nlm.nih.gov production


12.1 Mechanism of Action
The nucleoside-modified mRNA in COMIRNATY is formulated in [INACTIVE INGREDIENTS], which enable delivery of the mRNA into host cells to allow expression of the SARS-CoV-2 S antigen. The vaccine elicits an immune response to the S antigen, which protects against COVID-19.
by Cat on Wed Jan 19th, 2022 at 11:32:29 PM EST
[ Parent ]
neither DailyMed nor DrugBank describe the one ACTIVE INGREDIENT, Tozinameran

which being "recobinant" RNA, should be identifiable by its genomic sequence.

by Cat on Wed Jan 19th, 2022 at 11:46:21 PM EST
[ Parent ]
by Cat on Sun Jan 23rd, 2022 at 04:42:17 PM EST
[ Parent ]


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