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Mutant SARS CoV-2 Ravages EU and East Coast

by Oui Tue May 5th, 2020 at 07:43:38 PM EST

Dr Bette Korber Los Álamos Lab mutations SARS CoV-2

Work in progress ...

More below the fold ..,

Scientists say a now-dominant strain of the coronavirus appears to be more contagious than original | LA Times |

Scientists have identified a new strain of the coronavirus that has become dominant worldwide and appears to be more contagious than the versions that spread in the early days of the COVID-19 pandemic, according to a new study led by scientists at Los Alamos National Laboratory.

The new strain appeared in February in Europe, migrated quickly to the East Coast of the United States and has been the dominant strain across the world since mid-March, the scientists wrote.

Wherever the new strain appeared, it quickly infected far more people than the earlier strains that came out of Wuhan, China, and within weeks it was the only strain that was prevalent in some nations, according to the report. The new strain's dominance over its predecessors demonstrates that it is more infectious, according to the report, though exactly why is not yet known.

The report was based on a computational analysis of more than 6,000 coronavirus sequences from around the world, collected by the Global Initiative for Sharing All Influenza Data, a public-private organization in Germany. Time and again, the analysis found the new version was transitioning to become dominant.

The Los Alamos team, assisted by scientists at Duke University and the University of Sheffield in England, identified 14 mutations. Those mutations occurred among the nearly 30,000 base pairs of RNA that other scientists say make up the coronavirus's genome. The report authors focused on a mutation called D614G, which is responsible for the change in the virus' spikes.

My recent diary ....

Global Void Called USA


Neil Ferguson: Government coronavirus adviser quits after breaking lockdown rules | The Independent |

by Oui on Tue May 5th, 2020 at 08:15:17 PM EST
by Oui on Fri May 8th, 2020 at 03:48:47 PM EST
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by Oui on Tue May 5th, 2020 at 08:42:18 PM EST
Labour's Rosena Allin-Khan has an epic response to anyone who thinks she needs to `watch her tone' - and it involves Cher | Pink News |

The shocking exchange caused outrage online as the public accused Hancock of patronising and gaslighting Allin-Khan, displaying a perfect example of the tone-policing that is commonly used to condescend to women and people of colour in politics.

"It's a classic control technique; shorthand for keep quiet woman. Fortunately Dr Allin-Khan stood her ground," one Twitter user wrote.

"Dr Allin-Khan's tone was dignified and suitably passionate for the severity of the subject," another added. "Unfortunately, a woman's passion is `unnecessary emotion' in the eyes of weak men."

'I will not watch my tone': Labour MP and doctor responds to health secretary's scolding over coronavirus testing figures | The Independent |

by Oui on Tue May 5th, 2020 at 08:57:08 PM EST
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by Oui on Tue May 5th, 2020 at 09:10:52 PM EST
Who needs a Covid-19 task force when it is capitalism that needs to be saved?

Index of Frank's Diaries
by Frank Schnittger (mail Frankschnittger at hot male dotty communists) on Wed May 6th, 2020 at 06:34:01 PM EST
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A running list of how President Trump is changing environmental policy | National Geographic |

There's an unlikely beneficiary of coronavirus: The planet | CNN News |

by Oui on Wed May 6th, 2020 at 08:00:01 PM EST
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"The Lady's Not For Turning"

by Oui on Wed May 6th, 2020 at 08:36:07 PM EST
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The Plan Is to Save Capital and Let the People Die
Whether Americans know it or not, their government is not working for them. Their government is working on behalf of capital. Humans are now a mere second-order, instrumental factor to be considered based on how it affects capital.

This is particularly tragic considering that, for countries with their own fiat currency such as the USA and the UK, capital can be created at will by the treasury/central bank of that country. Granted the USA has more leeway in this regard due to the weight of its currency in the international market. But the government of such a country can always purchase any good or service that is produced in their country without inflationary effect provided such purchases do not produce shortages of resources.

In both the USA and the UK this highlights the folly of having 'off-shored' so much of their manufacturing, as that factor decreases the latitude of the available response. In both countries the financial sectors have effectively devoured much of the former productive capacity of the country as part of a scheme to funnel ever more of the nations' productivity into their hands. A move to rebalance these economies is in order, especially for basics such as health care supplies.

Of course a major motive for the shift to 'off-shore' manufacturing was to confound the ability of nation states to tax and control trans-national corporations. It was for these reasons that 'captains of industry' invested so heavily in the political processes. Through purchase or rent of the apparatus of national government they get laws favorable to their interests, regardless of how deleterious the effects of those changes are on the domestic population.

The other factor at play in this dilemma is the fact that competing capitalists keep score in terms of the national currencies. Their goals are to acquire as much wealth as the can, but that wealth is denominated in national currencies. So, while intellectually they might understand that governments can and do create money at will, emotionally, they cannot help but see government spending on anything other than benefits to them as pernicious.

These factors come into sharp focus when the conflict comes down to saving lives at the expense of perceived dilution of the value of money. Better to be king of a shitpile than an equal in a paradise.

"It is not necessary to have hope in order to persevere."

by ARGeezer (ARGeezer a in a circle eurotrib daught com) on Sun May 10th, 2020 at 03:15:37 PM EST
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COVID-19: The CIDRAP Viewpoint -- by Osterholm et al

by Oui on Wed May 6th, 2020 at 03:28:42 AM EST
by Oui on Thu May 7th, 2020 at 01:39:31 PM EST
by Oui on Thu May 7th, 2020 at 01:41:04 PM EST
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Yesterday, Gov. "Mag-lev" Hogan accepted "test vaccine" donations from Pfizer-Biontech JV laboratory and 1.6K doses of Right-to-Try remdesivir from Gilead to be ahh deployed to undisclosed medical ahh facilities in Montgomery and Prince Georges counties whose confirmed case loads 6,032 and 8,516 respectively, seem to predicate optimal, if statistically insignificant, clinical trial outcomes.

COINCIDENTALLY, re-print of 2017 research, Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses, is circulating under separate cover with Gilead's brand name PR. Ignorance of prior NIAIID/DOD relationship to R&D and marketing, "EBOV" trial on humans across African nations since 1979 at least, and indeterminate efficacy of this "wide-spectrum" formula are already "priced" into shareholders' ROI in CARES Act appropriations.

The Institute for Clinical and Economic Review (ICER), which assesses effectiveness of drugs to determine appropriate prices, suggested a maximum price of $4,500 per 10-day treatment course based on the preliminary evidence of how much patients benefited in a clinical trial. Consumer advocacy group Public Citizen on Monday said remdesivir should be priced at $1 per day of treatment, since "that is more than the cost of manufacturing at scale with a reasonable profit to Gilead."

Some Wall Street investors expect Gilead to come in at $4,000 per patient or higher to make a profit above remdesivir's development cost [?!], which Gilead estimates at about $1 billion.

Recall: GS-5734 is USAMRIID's patent identifier for remdesivir (brand name)

by Cat on Thu May 7th, 2020 at 05:58:36 PM EST
by Oui on Fri May 8th, 2020 at 07:05:37 AM EST
Democrats demand details of Trump Organization requests for UK coronavirus aid | The Guardian |

Trump Doonbeg resort taps Government wage subsidy scheme | The Irish Times |

The Trump Organization is among the companies seeking Government help to cover wages at its Irish operations, availing of the wage subsidy scheme at its Trump International Golf Links and Hotel in Doonbeg, Co Clare.

The group is also tapping UK government bailout money to cover payments to bar staff, bagpipers and other employees furloughed from its golf properties.

Overseas businesses owned by US president Donald Trump can tap government funds meant to help retain workers. In the US, by contrast, they're specifically written out of the enormous US economic relief package. The result is a potentially stark gap between how workers in different countries may weather the crisis, even within the same global operation.

In the US, roughly 2,000 employees dismissed from Trump golf courses and hotels will have to line up with millions of others to apply for unemployment payments.

by Oui on Fri May 8th, 2020 at 07:41:19 AM EST
by Oui on Fri May 8th, 2020 at 03:42:20 PM EST
by Oui on Fri May 8th, 2020 at 07:36:37 PM EST
Katie Miller tests positive.

From my diary - From a Fringe to a Presidency - White Supremacy

by Oui on Fri May 8th, 2020 at 09:38:17 PM EST

White House Virus Task Force members face quarantine | SFgate |

    Fauci, the director of the National Institute of Allergy and Infectious Diseases and a leading member of the task force, has become nationally known for his simple and direct explanations to the public about the coronavirus and COVID-19, the disease it causes. Also quarantining are Dr. Robert Redfield, director of the Centers for Disease Control and Prevention, and the commissioner of the Food and Drug Administration, Stephen Hahn.
by Oui on Sun May 10th, 2020 at 06:55:22 AM EST
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The Fantasy World to keep merits of the Capitalist Empire in place.

Propaganda in time of war - WWII - Vietnam War - Subversion in the America's - Kosovo - Iraq - Iran - Libya - Syria - Russia ... soon China.

The unknown coronavirus - invisible to the eye - transgressed the human cell and through it's hosts traveled the globe into the heart of the Empire: the residence of the Great Leader in the White House. Builder of Walls, BIG economy, greatest armada of military might on land, sea, sky and space.

Leader has no idea what to do with SARS CoV-2 and leads by pointing to his head and gut feelings. We Americans are doomed.

Election Year 2020 -- TIME's Person of the Year frontcover will undoubtedly be ...

by Oui on Sat May 9th, 2020 at 09:14:06 AM EST
The "China virus" knows no borders, race, wealth or White House entry checks. It's invaded the premises on 1600 Pennsylvania Avenue uninvited and is carried into the Oval Office by hosts, the workplace of the most powerful leader on Planet Earth. The bluff and bruhaha of Trump in spite, the virus is sitting close by near his desk where the sign "the buck stops here" has been replaced by a photo of himself.

CDC director self-quarantining after exposure to person at the White House who tested positive for Covid-19 | CNN News |

White House deputy press secretary Judd Deere declined to confirm the report that Redfield will self-quarantine, but he said the physician to the President and White House operations officials "continue to work closely to ensure every precaution is taken to keep the President, First Family and the entire White House Complex safe and healthy."

"The President's physician and White House Operations continue to work closely to ensure every precaution is taken to keep the President, First Family and the entire White House Complex safe and healthy at all times. In addition to social distancing, daily temperature checks and symptom histories, hand sanitizer, and regular deep cleaning of all work spaces, every staff member in close proximity to the president and vice president is being tested daily for COVID-19 as well as any guests," Deere said in a statement.

Dr. Stephen Hahn, the commissioner of the Food and Drug Administration, also began to self-quarantine Friday after being exposed to a person at the White House who tested positive.

Coronavirus in the US: Top White House officials buried CDC report for coronavirus reopening

Testing by itself, even 100% testing is not enough, if you don't do social distancing and wear protective face masks in close quarters. Simple guidelines people! :-)

Related reading ...

Trump falsely declares kids safe from coronavirus: AP Fact Check
3 NY Deaths Linked to Rare COVID-Related Inflammatory Illness, At Least 73 Children Sick | NBC New York |

by Oui on Sun May 10th, 2020 at 07:39:43 AM EST
by Oui on Sun May 10th, 2020 at 01:28:17 PM EST
by Oui on Fri May 15th, 2020 at 08:18:16 PM EST
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by Oui on Sun May 10th, 2020 at 01:32:44 PM EST
by Oui on Sun May 10th, 2020 at 01:37:26 PM EST
by Oui on Sun May 10th, 2020 at 01:44:54 PM EST
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by Oui on Sun May 10th, 2020 at 07:40:35 PM EST
by Oui on Sun May 10th, 2020 at 07:42:24 PM EST
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by Oui on Sun May 10th, 2020 at 07:44:06 PM EST
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by Oui on Mon May 11th, 2020 at 05:24:14 AM EST
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by Oui on Mon May 11th, 2020 at 09:02:10 AM EST
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I would still considere both States with failed leadership on track to be failed States.

by Oui on Sun May 10th, 2020 at 08:17:28 PM EST
by Oui on Sun May 10th, 2020 at 08:22:44 PM EST
Hawaii 'Flatten the Curve' Strategy on Mid-March

by Oui on Mon May 11th, 2020 at 06:26:40 AM EST
by Oui on Mon May 11th, 2020 at 06:34:12 AM EST
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Anger in Korea after nightclubber spreads virus | Asia Times |

Concern is spreading across South Korea, where social distancing was officially relaxed this week, about a potential explosion of infections after a 31-year old man who tested positive for Covid-19 on Thursday was found to have visited five bars and nightclubs last weekend.

By Friday morning, at least 14 of the man's contacts had tested positive, according to the Korea Centers for Disease Control and Prevention. The man had visited the nightspots last weekend and some media suggested that as many as 2,000 people who had been at the venues could be at risk.

South Korea LGBT stigma complicates coronavirus testing as new cases rise | SCMP |

by Oui on Mon May 11th, 2020 at 11:33:37 AM EST
by Oui on Wed May 13th, 2020 at 09:39:46 AM EST
This is why you will never see an effective vaccine. It mutates too fast. That's also why we don't have a vaccine for the common cold which is related.

We need a CURE!

by StillInTheWilderness on Wed May 13th, 2020 at 04:57:55 PM EST
by Oui on Thu May 14th, 2020 at 06:24:22 AM EST
It'n now proven the highly contagious SARS CoV-2 spreads further in a minimum of time compared to the SARS or MERS virus. Its characteristic to mutate may cause SARS CoV-2 to be around for years as an endemic disease.

Talking can spread more than 1,000 COVID-19 particles per minute, study finds | Miami Herald |

It's known that the new coronavirus can spread by droplets released from coughs and sneezes, but new research says those coming from speech can be just as harmful in transmitting the disease, even from people who aren't showing symptoms.

The study suggests that normal speaking in closed environments such as homes and restaurants can contribute "substantially" to the spread of COVID-19 -- the disease the coronavirus causes -- according to the researchers.

The paper was published Wednesday in the journal Proceedings of the National Academy of Sciences.

To measure the size and quantity of speech-related droplets, the researchers had people repeat the phrase "stay healthy" in a loud voice and then used a "highly sensitive" sheet of laser light to scan the droplets in the air.

The results showed that about 2,600 droplets are expelled from a person's mouth per second, the study said.

What's more, the researchers said one minute of loud speaking could generate more than 1,000 virus-containing droplets that could float in the air for 8 minutes or longer.

by Oui on Thu May 14th, 2020 at 06:57:32 AM EST
Luke 'the Russians Did It' Harding about a novel virus ...

by Oui on Fri May 15th, 2020 at 09:54:25 PM EST
"... reports of pressure on US doctors not to report deaths as Covid unless confirmed by test, and tests not being ordered for the deceased." [Front page comment Frank Schnittger]

In Dutch hospitals and healthcare a similar policy except for "pressure" on doctors. In the UK there is immense pressure on medical staff and nurses NOT to complain of poor protection in facilities and lack of PPE.

Overall in the "herd immunity" nations, the elderly and specifically the those in care or nursing homes were left to become infected and face an early, horrible death. I can see no other factor than that it was deliberate. Mitigating the virus spreading through lockdown measures, but leaving nurses vulnerable and by family members visiting the elderly, spread the virus into these facilities. in the month of March, it were the hospital workers who were infected, not being tested, and hospitals became the source of clusters.

Setting the stage to remove the elderly from healthcare and costs - permanently!

Dutch IC Protocol: From Code Red to Black  | March 13 !! |

Only the Medical Facilities of the University in Groningen caught the coronavirus in an early stage through testing, testing, testing. This was NOT supported by the official national CDC organization in the Netherlands, the RIVM.

Due to a lack of insight by the media, journalists and members of Dutch Parliament, no critical questions are asked and PM Mark Rutte rides high on the waves of popularity in polls. He's just as a big a$Shole as PM Boris Johnson in the UK, but manages his PR and presentation better. A young team keeping criticism and tough questions at a comfortable distance.

Math : The Numbers -- Herd Policy A Failure | March 23 |

Questions SP member Dutch parliament angers PM Mark Rutte, shouts out ...

    PM Rutte in anger shouts out: "You cross a boundary of decency." Up till now the PM could send replies to written questions. In the morning, the Commission on Health had a meeting with RIVM Head van Dissel. Members of parliament were well prepared, better than the situation of testing and stock of PPE for first line medical workers.

The House of Representatives at work

by Oui on Sat May 16th, 2020 at 09:37:56 AM EST
Transcript Meeting Dutch Parliament on April 22, 2020: Ms Marijnissen (SP):

Thank you, chairwoman. In one nursing home in Amsterdam, 31 residents have now died of corona. 48 health care providers are infected, one of which is in intensive care. The health care inspector says that the nursing home actually did everything to keep the virus out as much as possible. However, it was also a factor that in the first weeks of the outbreak of the virus there were insufficient protective materials for the care providers. Imagine the grief of 31 families losing a father or a mother. But also imagine the fear of that care staff. They go to work every day with fear in their bodies, fear of becoming infected themselves and fear of infecting the people to whom you would like to provide care. I really have immense respect for the work these people are doing right now. But I also find it almost inhuman that we ask them. When we hear that the curve in the nursing homes is not leveling off, as Van Dissel (RIVM) says, and when we hear from the workers union CNV that they are very concerned about care staff who become ill on a massive scale - last month there was an increase of 40% - then my question to the minister is: how does he view the situation in Dutch nursing homes?

If I listen to the cabinet in this way, I have the idea that you can better be a smartphone looking for an app at this time than a healthcare provider looking for a mask. I would love it if the enthusiasm and enthusiasm with which the app is thought about and worked on, would also be there for starting up the production of protective materials domestically.

The Prime Minister is now getting angry, I understand, chairman. He shouts: "You are crossing a line". But I think we cross a line every day by asking those people to do their jobs without adequate protective equipment. Then the prime minister may get angry and shout, but I think we will cross that line.

This brings me to the testing capacity in the laboratories. For weeks we have been asking why it is not possible to fully utilize that test capacity. We hear from laboratories that there is more space to test, but it does not work. So my question is: how is that possible? Another question concerns the capacity of the GGD. Is it sufficient? That has already been asked. How is it possible that there is not yet an order with the GGD to put everything in place to conduct large-scale contact research?


Production facilities in The Netherlands geared up for delivering surgical face masks

by Oui on Sat May 16th, 2020 at 09:39:36 AM EST
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From my diary - From Outbreak to a Global Pandemic



All three Conservative Party leaders Trump - Johnson - Rutte were proponents of "herd immunity" to favor saving the economy over a large number of deaths in the population. These men in power carry a burden of responsibility for suffering and unnecessary deaths. The coronavirus lives and is carried around the globe by hosts. Capitalism and Narcissistic leaders: LIVES DON'T MATTER.

by Oui on Sat May 16th, 2020 at 09:48:24 AM EST
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Trump On Healthcare Workers: 'They're Running Into Death Just Like Soldiers Run Into Bullets' | Forbes |

by Oui on Sat May 16th, 2020 at 09:54:48 AM EST
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by Oui on Tue May 19th, 2020 at 06:06:48 PM EST
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by Oui on Tue May 19th, 2020 at 06:11:18 PM EST
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The Mathematics of Predicting the Course of the Coronavirus | Wired - March 30, 2020 |

by Oui on Sun May 17th, 2020 at 07:26:40 PM EST
Grading the States' Coronavirus Control, illustrated by NY Yella Cake
I recently wrote a Twitter thread (5/12/20) about another New York Times graphic feature that was a good idea, strangely executed.

The good idea, which appears on the Times` "Coronavirus in the US" page, is to sort states in terms of how well they're controlling the coronavirus outbreak, using graphs of the daily count of new cases in each state. This seems like a good choice of metric and a useful thing to keep track of, especially given how fragmented the US response has been.

by Cat on Mon May 18th, 2020 at 01:13:10 AM EST
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by Oui on Mon May 18th, 2020 at 08:44:37 AM EST
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Official findings add to concerns about Sweden's laissez-faire strategy towards the pandemic

Just 7.3% of Stockholm's inhabitants had developed Covid-19 antibodies by the end of April, according to a study, raising concerns that the country's light-touch approach to the coronavirus may not be helping it build up broad immunity.

Björn Olsen, a professor of infectious medicine at Uppsala University, said herd immunity was a "dangerous and unrealistic" approach. "I think herd immunity is a long way off, if we ever reach it," he told Reuters after the release of the antibody findings.

Tegnell had denied herd immunity is a goal in itself, saying Sweden aims instead to slow the spread of the virus enough for health services to cope.

The development of COVID-19 deaths in Sweden

Bereaved families call for urgent inquiry into UK Covid-19 response

by Oui on Thu May 21st, 2020 at 07:46:04 PM EST

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