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Latest Data Omicron Variant

by Oui Tue Nov 30th, 2021 at 10:35:37 AM EST

From my earlier posts here ...

WHO Alert for High Risk Omicron Variant

WHO: Enhancing Readiness for Omicron (B.1.1.529): Technical Brief and Priority Actions for Member States

The Omicron virus has high transmissibility and will by-pass or breakthrough the previous (natural) immunity of humans. May have some effect to limit severity of illness and certainly low mortality rate. For the elderly above 80 years the effect can be severe. The Dutch have not started the booster jab campaign and already the breakthrough infection with the Delta variant turns out to be very deadly. Forty percent of nursery homes have infections and the mortality rate is 22% !!
Greatest unknown are the longterm effects for young persons.

Readiness to mitigate the transmission is most important ... we've known the basics for nearly two years and have not complied with wisdom.

Very worrisome ...

The Effects of COVID-19 on the Placenta During Pregnancy

Today an report from Erasmus MC in Rotterdam

Campaign to battle SARS CoV-2 Equally

Prognosis

Moderna boss says vaccines likely no match for Omicron: FT | France24 |

Existing Covid-19 jabs will struggle against the Omicron variant and it will take months to develop a new shot that works, the head of US vaccine manufacturer Moderna has told the Financial Times.

Pfizer takes three months to have new vaccine on the market ...

FDA moving to authorize Pfizer booster for 16-, 17-year-olds - report | JPost |

Herd Immunity starting with toddlers < 2 year-olds

231 heart inflammation cases follow Covid jabs: Side effect research center

Israel under attack

Regarding the first doctor, the hospital said in a statement on Monday that “the doctor is vaccinated with three doses of the coronavirus vaccine, his condition is mild and he is improving,” adding that he does not need any medical attention.

A cardiologist, the doctor performed several catheterizations and attended at least two other large events before experiencing symptoms and testing. All of the doctor's contacts have been alerted and are being tested. The second doctor, also a cardiologist, was likewise fully vaccinated.

Science Corner

The Old Magic Magician

A follow-up diary how Omicron manages to split the Tory leadership and the backbenchers, dare we mention the folks in their constituencies?

The spread of Omicron Update here ,..

Display:
Latest Data Omicron Variant | 155 comments (155 topical, 0 editorial, 0 hidden)
Re: Latest Data Omicron Variant (none / 0)


'Sapere aude'
by Oui (Oui) on Tue Nov 30th, 2021 at 08:06:21 PM EST
Omicron Likely to Replace the Delta Variant (none / 0)


'Sapere aude'
by Oui (Oui) on Tue Nov 30th, 2021 at 08:18:54 PM EST
"competition" (none / 0)
the proposition is illogical for a number of uhhh reasoned calculations of viral evolution since "pre-alpha" generation, but not least of which "official" efficacy of current pharmaceutical and non-pharmaceutical interventions to CONTAIN "silent spreaders" in all of Africa, Russia, and China.

Indeed, US press duly noted that Joe's ban of travel to and from the 7 (or 8) "hot spots" excludes US citizens. Evidently, Joe's experts are unconcerned about the virulence (transmissibility or "grave danger") of their EXPOSURE to either this SARS-CoV-2 variant or any other variant. I idly wonder though, when the feds will reveal the mandate to quarantine those repatriated Americans at US military bases for an unspecified period.

archived Fri Mar 6th, 2020

by Cat on Fri Dec 3rd, 2021 at 01:46:33 PM EST
[ Parent ]
Sequence of Omicron Variant South Africa - Nov 25 (none / 0)


'Sapere aude'
by Oui (Oui) on Fri Dec 31st, 2021 at 09:09:51 AM EST
[ Parent ]
National Security Apparatus v. Omicron Scourge (none / 0)


'Sapere aude'
by Oui (Oui) on Tue Nov 30th, 2021 at 08:22:19 PM EST
Austria Hospitals In Code Black (none / 0)


'Sapere aude'
by Oui (Oui) on Wed Dec 1st, 2021 at 01:33:54 PM EST
Re: Austria Hospitals In Code Black (none / 0)
Corona infections skyrocket after "freedom tour" of the FPÖ in Carinthia

The "freedom tour" of FPÖ chairman Herbert Kickl in Carinthia at the beginning of November, which took him from Wolfsberg to Gmünd, caused heated debates. A major FPÖ event took place in Wolfsberg on November 5th. In the near future, the number of infections in the district skyrocketed; the seven-day incidence is currently over 2000, making the district the sad leader in Austria.

Singer of the "Fidelen Mölltaler" died

There was also material for debate after it became known that the singer of the folk music group "Die Fidelen Mölltaler", Ludwig "Lucky" Ladstätter, died on Monday after a two-week fight against Corona in the Wolfsberg hospital. He had also attended the FPÖ event, as shown by a photo of him with Kickl, which he himself posted on Instagram.

According to information from Kabeg, the state hospital in Wolfsberg is working at full capacity. Since all hospitals in the state cooperate with intensive care patients, the question of whether the intensive care unit in Wolfsberg is overloaded cannot be answered that way. 57 people in Carinthia are currently receiving intensive medical care due to corona.



'Sapere aude'
by Oui (Oui) on Wed Dec 1st, 2021 at 03:07:59 PM EST
[ Parent ]
Re: Austria Hospitals In Code Black (none / 0)

The in Basel known Omikron-Fall is it a 19 year old high school student. He is a student at the Kirschgarten High School. The source of infection is unknown and it has no travel activity given in advance, informs the Basel health department. Of the fully vaccinated high school student have mild symptoms, it was said. The case was discovered with the regular mass testing in schools. The subsequent individual test was sequenced and the omicron virus was confirmed.

During the contagious period he was in contact with his class as well as with the choir and orchestra with whom he had a performance last week. The contact tracing team has informed the school management, parents and other private contact persons of the student. Around 100 people have to be in quarantine for ten days.



'Sapere aude'
by Oui (Oui) on Wed Dec 1st, 2021 at 03:08:47 PM EST
[ Parent ]
You can't fix stupid. (none / 1)
S-dropout has entered the room of "what we know now" that "we" are testing only for OMICROM variant out of innumerable SARS-CoV-2 variants with innumerable dip-stick home antibody and high-frequency lab-confirmed RT-PCR tests...while pre-alpha, alpha, and DELTA "community spread" fades into the exhaust of "excess deaths" and passe as well as passenger plane, train, and automobile travel.
by Cat on Wed Dec 1st, 2021 at 05:43:25 PM EST
Re: You can't fix stupid. (none / 0)
The hands down winners ... no comparison

UK Health Services

A matter of National Security.

'Sapere aude'

by Oui (Oui) on Wed Dec 1st, 2021 at 06:13:22 PM EST
[ Parent ]
Re: You can't fix stupid. (none / 0)
2. Delta remains the predominant variant accounting for approximately 99.8% of
sequenced cases in England as of 25 October 2021.
by Cat on Wed Dec 1st, 2021 at 07:22:24 PM EST
[ Parent ]
Re: You can't fix stupid. (none / 0)
regular SARS-CoV-2 has entered the room.

No cream. No sugar.

by Cat on Wed Dec 1st, 2021 at 07:41:26 PM EST
[ Parent ]
Re: Latest Data (none / 0)
I detect a communication problem.

in Gain-of-Function Research on HPAI H5N1 Viruses: Welcome and Introductory Remarks (2013), feat. yer boy Fauci
by Cat on Wed Dec 1st, 2021 at 07:05:07 PM EST
Re: Latest Data (none / 0)
by Cat on Wed Dec 1st, 2021 at 07:49:49 PM EST
[ Parent ]
Re: Latest Data (none / 0)
Time to 'think about mandatory vaccination': Urusla
She noted that "if you look at the numbers we have now, 77% of the adults in the European Union vaccinated, or if you take the whole population, it's 66% -- and this means one-third of the European population is not vaccinated, these are 150 million people".
[...]
While the European Commission pre-purchased Covid vaccines for use in the EU, von der Leyen emphasised that the individual countries had the responsibility on how their vaccination programmes were done.
by Cat on Wed Dec 1st, 2021 at 07:53:39 PM EST
[ Parent ]
Re: Latest Data (none / 0)
Who in the EC is looking into the Cuban vaccines, to see if they are really safe for 2-year old children?
by gk (gk (gk quattro due due sette @gmail.com)) on Wed Dec 1st, 2021 at 08:02:43 PM EST
[ Parent ]
Re: Latest Data (4.00 / 2)
Probably nobody. It's Cuban, after all.

It's also a conjugate vaccine, which have been in use almost 100 years now. So it's a pretty well known technology. Apparently the Cubans have also vaccinated close to two million kids with their vaccine since summer, and it seems to be both safe and effective.

And this is according to Nature. I doubt the sciency stuff doesn't matter, when we have "values" to defend.

by pelgus on Wed Dec 1st, 2021 at 08:48:16 PM EST
[ Parent ]
Re: Latest Data (none / 0)
What about the US? We're told that Biden and Fauci are only going by the science.
by gk (gk (gk quattro due due sette @gmail.com)) on Thu Dec 2nd, 2021 at 06:13:16 PM EST
[ Parent ]
Re: Latest Data (none / 1)
We were also told Iraq imported Nigerian yellow cake uranium to build nukes, was making chemical weapons, and had mobile bio-warfare laboratories.

She believed in nothing; only her skepticism kept her from being an atheist. -- Jean-Paul Sartre
by ATinNM on Sun Dec 5th, 2021 at 04:18:17 PM EST
[ Parent ]
Re: Latest Data (none / 0)
I'm not so sure that is a fair comparison though
by asdf on Thu Dec 9th, 2021 at 05:31:06 PM EST
[ Parent ]
Re: Latest Data (none / 0)
Bush years and role of Big Pharma ... the 9/11 event supported anti-terror regulation to detriment of civil rights and personal freedom. The anthrax letters were quite puzzling ... fear of WMD and radioactive material scare played indeed a large role.

Big Pharma and anthrax scare or anti-terror in general

Postal Anthrax Aftermath: Has Biodefense Spending Made Us Safer? | Scientific American - Nov. 1, 2008 |

NIAID director Anthony S. Fauci set an ambitious goal.

From Covid-19 vaccine mix-up between AstraZeneca and Pfizer BioNTech production ...

Emergent BioSolutions anthrax attacks in the United States. ... budget more typical of some big pharmaceutical companies.


'Sapere aude'

by Oui (Oui) on Thu Dec 9th, 2021 at 06:20:00 PM EST
[ Parent ]
Re: Latest Data (none / 0)
and Havana, Miami Syndrome
by Cat on Fri Dec 3rd, 2021 at 01:48:59 PM EST
[ Parent ]
Re: Latest Data (none / 1)
The Cuban Abdala vaccine has yet to receive WHO approval, a requirement for many countries.  Viet Nam, Venezuela, and Honduras either have or are in the process of purchasing the vaccine.  Practically speaking, Latin American and African countries are desperate to get vaccines and many may go ahead with purchase.

Cuba's bet on home-grown COVID vaccines is paying off: Preprint data show that a three-dose combo of Soberana jabs has 92.4% efficacy in clinical trials

When the COVID-19 pandemic began, Cuba decided not to wait on the rest of the world to develop vaccines. The United States' 60-year-old economic embargo against the country, which prevents US-made products from being exported there, would make it difficult for Cuba to acquire vaccines and therapies, researchers and officials knew. "It was best, for protecting our population, to be independent," says Vicente Vérez Bencomo, director-general of the Finlay Institute of Vaccines in Havana.

So the Finlay Institute and Cuba's other state-run biotechnology centres started developing their own COVID-19 vaccines in the hope that at least one of them would be effective. Their bet seems to be paying off: in a 6 November preprint published on medRxiv1, Vérez Bencomo and his colleagues report that one of the institute's vaccines, Soberana 02, is more than 90% effective in protecting against symptomatic COVID-19 infection when used in combination with a related vaccine. Importantly, the combination seems to be effective against the highly transmissible Delta variant of the coronavirus SARS-CoV-2, which has caused surges in hospitalizations and death across the world and now accounts for nearly all COVID-19 cases in Cuba

As an aside, WHO is forecasting a shortage of syringes so it's completely pointless to stockpile vaccines that will only sit there and rot. Which would be par for the course since historically ~50% of vaccines sent to the Third World pass their 'Use By' date due to logistic barriers.

She believed in nothing; only her skepticism kept her from being an atheist. -- Jean-Paul Sartre

by ATinNM on Sun Dec 5th, 2021 at 04:15:25 PM EST
[ Parent ]
Re: Latest Data Omicron Variant (none / 1)


'Sapere aude'
by Oui (Oui) on Thu Dec 2nd, 2021 at 08:23:48 AM EST
Re: Latest Data Omicron Variant (none / 0)
UK "community PCR testing": Is this a euphemism for ill-conceived, cost-sensitive CDC pool testing "strategy" introduced in 2020?
by Cat on Sat Dec 4th, 2021 at 05:53:50 PM EST
[ Parent ]
Re: Latest Data Omicron Variant (none / 0)


'Sapere aude'
by Oui (Oui) on Thu Dec 2nd, 2021 at 12:14:25 PM EST
Re: Latest Data Omicron Variant (none / 0)
Extreme surge in South Africa from 300 to over 8,500 cases per day ...

COVID-19: Omicron can evade some immunity, not all, data from South Africa shows

'Sapere aude'

by Oui (Oui) on Thu Dec 2nd, 2021 at 12:15:15 PM EST
Re: Latest Data Omicron Variant (none / 0)


'Sapere aude'
by Oui (Oui) on Thu Dec 2nd, 2021 at 07:05:35 PM EST
Seems bad (none / 1)
by generic on Thu Dec 2nd, 2021 at 07:09:27 PM EST
Re: Seems bad (none / 0)
except for conspicuous breaks in these series, omissions of morbidity and mortality curves, and omicron "detection" appears to have occurred at the same time as delta, alpha, or "pre-alpha".
by Cat on Fri Dec 3rd, 2021 at 02:03:39 PM EST
[ Parent ]
Re: Seems bad (none / 0)
Where would you get Omicron morbidity curves? It's been around for barely a week. If I'm not completely talking out of my ass this curve is based on the FT's version, though I haven't looked up what their specific method was for determining the start of a wave.
by generic on Fri Dec 3rd, 2021 at 09:32:41 PM EST
[ Parent ]
Re: Seems bad (none / 1)
Graph is to illustrate the rapid increase of each variant ...

Omicron SARS-CoV-2 variant: a new chapter in the COVID-19 pandemic | The Lancet |

The first sequenced omicron case was reported from Botswana on Nov 11, 2021, and a few days later another sequenced case was reported from Hong Kong in a traveller from South Africa.

Several sequences from South Africa followed, after initial identification that the new variant was associated with an S-gene target failure on a specific PCR assay because of a 69-70del deletion, similar to that observed with the alpha variant.

The earliest known case of omicron in South Africa was a patient diagnosed with COVID-19 on Nov 9, 2021, although it is probable that there were unidentified cases in several countries across the world before then. In South Africa, the mean number of 280 COVID-19 cases per day in the week before the detection of omicron increased to 800 cases per day in the following week, partly attributed to increased surveillance.

COVID-19 cases are increasing rapidly in the Gauteng province of South Africa; the early doubling time in the fourth wave is higher than that of the previous three waves (figure).

Omicron vs. Delta: Comparing COVID's most worrisome variants

Emergence

Delta: First identified in India in December 2020, Delta is presumed to have come from someone whose immune system was suppressed, perhaps due to medications or an illness such as HIV/AIDS.

Progressive Increase in Virulence of Novel SARS-CoV-2 Variants in Ontario, Canada

The period from February to June 2021 was one during which initial wild-type SARS-CoV-2 strains were supplanted in Ontario, Canada, first by variants of concern (VOC) with the N501Y mutation (Alpha/B1.1.17, Beta/B.1.351 and Gamma/P.1 variants), and then by the Delta/B.1.617 variant. The increased transmissibility of these VOCs has been documented but data for increased virulence is limited. We used Ontario's COVID-19 case data to evaluate the virulence of these VOCs compared to non-VOC SARS-CoV-2 infections, as measured by risk of hospitalization, intensive care unit (ICU) admission, and death.

Deaths are limited as gratitude for many patients already vaccinated before being infected by the Delta variant. However as I stated above, for the elderly in nursing homes, once infected by the Delta variant to mortality rate is above 20%. The Omicron mutant will be devastating for the unvaccinated group of the population: toddlers and young children under 12 years old.

'Sapere aude'

by Oui (Oui) on Fri Dec 3rd, 2021 at 10:26:07 PM EST
[ Parent ]
Covid Deaths: Dutch Lack of Decision Makers (none / 0)

Many countries have started booster jabs by early September, not the Dutch. In November 3,500 excess deaths, funeral parlors can barely handle the numbers. In the province of Limburg excess deaths reached 53%, the Carnival province has the worst rate of Covid-19 infections. Dutch policy in The Hague gives priority to individual "freedom", respects rightwing anti-vaxxers and sacrifices the elderly. In 40% of the nursing homes, the Delta variant ravages the population. The anti-vaxxers makes it clear by statements the want "quality" of life and will not heed the mitigation rules in society. The anonymous killers.

Translation:
Do I want to add years to my life or add life to my years?

Do I want to grow old safely for the rest of my life, or do I want to be able to go outside in freedom with all the risks that life has in store for me?

A$$hole ... who gives a sh*t about you when you don't care about a large group in society. Wish you a fun ending.

Booster jabs with Belgium compared ... 15.6% to the Netherlands 1.5%

'Sapere aude'

by Oui (Oui) on Fri Dec 3rd, 2021 at 07:54:59 AM EST
Re: Latest Data Omicron Variant (none / 1)
We'll all be South African in the end.
But not before Christmas, please.

It is rightly acknowledged that people of faith have no monopoly of virtue - Queen Elizabeth II
by eurogreen on Fri Dec 3rd, 2021 at 03:56:15 PM EST
Re: Latest Data Omicron Variant (none / 1)
South Africa
In South Africa, in the week since it alerted the world of the new Covid variant, infections have spread faster than in the country's three previous waves. Wassila Jassat, from the National Institute for Communicable Diseases (NICD), said: "We've seen quite a sharp increase across all age groups, particularly in the under fives," referring to hospitalisations.
Why are we not looking into the Cuban vaccine?
by gk (gk (gk quattro due due sette @gmail.com)) on Fri Dec 3rd, 2021 at 05:52:33 PM EST
[ Parent ]
Gauteng (none / 0)


'Sapere aude'
by Oui (Oui) on Fri Dec 3rd, 2021 at 08:46:12 PM EST
Re: Gauteng (none / 0)


'Sapere aude'
by Oui (Oui) on Fri Dec 3rd, 2021 at 08:47:42 PM EST
[ Parent ]
Omicron Variant Harbors Unique Insertion Mutation (none / 0)
Omicron variant of SARS-CoV-2 harbors a unique insertion mutation of putative viral or human genomic origin

The emergence of a heavily mutated SARS-CoV-2 variant (B.1.1.529, Omicron) and it's spread to 6 continents within a week of initial discovery has set off a global public health alarm. Characterizing the mutational profile of Omicron is necessary to interpret its shared or distinctive clinical phenotypes with other SARS-CoV-2 variants.

We compared the mutations of Omicron with prior variants of concern (Alpha, Beta, Gamma, Delta), variants of interest (Lambda, Mu, Eta, Iota and Kappa), and all 1523 SARS-CoV-2 lineages constituting 5.4 million SARS-CoV-2 genomes. Omicron's Spike protein has 26 amino acid mutations (23 substitutions, two deletions and one insertion) that are distinct compared to other variants of concern. Whereas the substitution and deletion mutations have appeared in previous SARS-CoV-2 lineages, the insertion mutation (ins214EPE) has not been previously observed in any SARS-CoV-2 lineage other than Omicron. The nucleotide sequence encoding for ins214EPE could have been acquired by template switching involving the genomes of other viruses that infect the same host cells as SARS-CoV-2 or the human transcriptome of host cells infected with SARS-CoV-2.

For instance, given recent clinical reports of co-infections in COVID-19 patients with seasonal coronaviruses (e.g. HCoV-229E), single cell RNA-sequencing data showing co-expression of the SARS-CoV-2 and HCoV-229E entry receptors (ACE2 and ANPEP) in respiratory and gastrointestinal cells, and HCoV genomes harboring sequences phomologous to the nucleotide sequence that encodes ins214EPE, it is plausible that the Omicron insertion could have evolved in a co-infected individual. There is a need to understand the function of the Omicron insertion and whether human host cells are being exploited by SARS-CoV-2 as an 'evolutionary sandbox' for host-virus and inter-viral genomic interplay.



'Sapere aude'
by Oui (Oui) on Sat Dec 4th, 2021 at 06:30:50 PM EST
Re: Latest Data Omicron Variant (none / 1)
As of Dec 5, 2021 there's little research being published.  What papers are out merely say, "it's concerning."  

Anecdotal reports and vacuous inanities from the Infotainment Mediums should be treated with extreme skepticism.  When they are right it's either by happenstance or the fact a stopped 12 hour clock is accurate twice a day.

She believed in nothing; only her skepticism kept her from being an atheist. -- Jean-Paul Sartre

by ATinNM on Sun Dec 5th, 2021 at 04:29:55 PM EST
Re: Latest Data Omicron Variant (none / 1)
Haven't you heard it's mIlD.

by generic on Sun Dec 5th, 2021 at 04:56:58 PM EST
[ Parent ]
Re: Latest Data Omicron Variant (none / 0)
Delta Plus variant

The Delta/ B.1.617.2 genome has 13 mutations (15 or 17 according to some sources, depending on whether more common mutations are included) which produce alterations in the amino-acid sequences of the proteins it encodes.

Press release: Vaccines highly effective against B.1.617.2 variant after 2 doses | UK Gov - May 22, 2021 |

New study by PHE shows for the first time that 2 doses of the COVID-19 vaccines are highly effective against the B.1.617.2 variant first identified in India.

The study found that, for the period from 5 April to 16 May:

  • the Pfizer-BioNTech vaccine was 88% effective against symptomatic disease from the B.1.617.2 variant 2 weeks after the second dose, compared to 93% effectiveness against the B.1.1.7 variant
  • 2 doses of the AstraZeneca vaccine were 60% effective against symptomatic disease from the B.1.617.2 variant compared to 66% effectiveness against the B.1.1.7 variant


'Sapere aude'
by Oui (Oui) on Sun Dec 5th, 2021 at 06:06:20 PM EST
[ Parent ]
archived OUI (none / 0)
13 mutations, huh.

Let's recap evolution of broadcast "threat" levels: about one week after South African beta collided with UK alpha, two weeks into First World BioNTech-Pfizer/Pfizer-BioNTech vaccine launch, and six months before 2021's delta-branded "wave" eliminated the 2020 variants of interest and concern.

ecdc | Rapid increase of a SARS-CoV-2 varient with multiple spike protein mutations observed in the United Kingdom, 20 Dec 2020

Over the last few weeks, the United Kingdom (UK) has faced a rapid increase in COVID-19 cases in South East England, leading to enhanced epidemiological and virological investigations. Analysis of viral genome sequence data identified a large proportion of cases belonged to a new single pylogenetic cluster. The new variant is defined by [9] spike protein mutations (deletion 69-70, deletion 144, N501Y, 4570D, D614G, P681H, T716I, 6982A, D1118H) present as well as mutations in other genomic regions. While it is known and expected that virus constantly change through mutation leading to the emergence of new variants, preliminary analysis in the UK suggests that this variant is significantly more transmissible than previously circulating variants, with an estimated potential to increase the reproductive number (R) by 0.4 or greater with an estimated increased transmissibility of up to 70%. This new variant has emerged at a time of the year when there has traditionally been increased family and social mixing. There is no indication at this point of increased infection severity associated with the new variant. A few cases with the new variant have to date been reported by Denmark and the Netherlands and, according to media reports, in Belgium.
Nextstrain.org classification, nomenclature, and their consequences, 6 Jan 2021
Finally, there is the issue where if 20A.EU1 did expand to >20% global frequency, it would be confusing to relabel it from 20A.EU1 to, for example, 20E.

Consequently, we propose an updated [nomenclature] strategy, where major (year-letter) clades are named when any of the following criteria are hit:

  1. A clade reaches >20% global frequency for 2 or more months
  2. A clade reaches >30% regional frequency for 2 or more months
  3. A VOC (`variant of concern') is recognized (applies currently to 501Y.V1 and 501Y.V220B , GISAID clade GR, lineage B.1.1.7. Phylogenetic analysis (Figure 4) reveals that there are very few intermediary forms between this variant and other circulating viruses reported to GISAID. The cluster differs by 29 nucleotide substitutions from the original Wuhan strain ["pre-alpha"], which is higher than current molecular clock estimates of around two substitutions per genome per month
What these facts communicate to me is not perfect information, but a formula for scheduling phase changes to government notices of PI + NPI rationale.

Moreover, given last weeks announcement of brand "omicron"--while C.1.2 (May 2020) doubtless slowly mutated as it circulated worldwide by commercial transit. Patent "outbreak" headlines and talking points a triggered by foregone conclusions to limited laboratory "detection" established place: global frequency >20%--absolute count over time--not newly "discovered" cases.

What irks me isn't so much errors in pseudo-scientific theory and practice , but the arrogance of First World "leadership" in pursuit of totally perverse domination.

by Cat on Mon Dec 6th, 2021 at 01:26:27 AM EST
[ Parent ]
There's this thing about liars ... (none / 1)
Scientists explore role of immunocompromised in generating Covid-19 variants wtaf
Who is the Omicron variant's patient zero? Detected for ["]the first time["] in South Africa, the variant formally known as B.1.1.529 sparked immediate concern in the international community. Indeed, Omicron's unprecedented number of mutations - more than 30 compared with the original strain of this coronavirus - present two potential threats: that it could be particularly contagious and that it might prove resistant to existing ["]vaccines["].

While governments around the world have set out to bolster restrictions to stem Omicron's spread, scientists have set about tracing the origins of the "super mutant" variant to understand how it came into being.

Among the theories put forward, some researchers are looking at mutations that appeared in one infected patient with a compromised immune system. Over the course of several months, they have studied the effect of a possible link between the emergence of variants of the highest concern [VOHC] and immune systems weakened in patients who are, for example, suffering from [CHF, COPD, diabetes I-III, herpes I-IV, MS, malaria, TB, obesity, etc], cancers [chemo drugs], waiting for an organ transplant [ACE inhibitors] or living with untreated HIV [?!]...

and there she blows ...
It is not the first time that South Africa has detected a new Covid-19 variant before anywhere else. Prior to the Omicron variant, two others had been dubbed "South African" variants before those names were changed; first, the Beta variant and then C.1.2.
They can't keep their stories straight.
"But that can be explained, first of all, by the fact that the country conducts a lot of sequencing, which is what enables it to identify variants on its soil," Maréchal explained. "It doesn't necessarily mean that the patient zero (of the Omicron variant) is in South Africa."
by Cat on Mon Dec 6th, 2021 at 01:58:39 AM EST
[ Parent ]
Look what dropped off P(0) front pages (none / 1)
China sticks to strict anti-virus policy as Omicron rages on across world
China has not detected such cases so far except in Hong Kong. Its health authority said the country will stick to its current anti-COVID strategy of preventing imported cases and a domestic resurgence, noting that such an approach is also effective against Omicron. "No matter how the virus mutates, it is still the novel coronavirus," said Zhang Wenhong, head of the Center for Infectious Diseases at the Shanghai-based Huashan Hospital of Fudan University.
[...]
All the local clustered cases in the COVID-19 resurgence since mid-October in China originated from overseas. The resurgence has spread to more than 20 provincial-level regions at its peak.

When dealing with these imported Delta variant cases, most regions managed to contain the outbreak within an incubation period of about 14 days. Aiming to contain an outbreak within an incubation period, relevant Chinese agencies have been making full use of the "golden period," the first 24 hours of a discovered case, to find those who were in close contact, isolate potentially infected individuals before the virus spreads, or before the infected person can transmit the virus.
[...]
Immediately after the three cases were reported, authorities there activated an emergency response. The local government ordered epidemiological investigators to arrive at the scene within two hours, complete the core investigations within four hours, and finish the epidemiological reports within 24 hours.

by Cat on Mon Dec 6th, 2021 at 02:14:21 AM EST
[ Parent ]
Re: Latest Data Omicron Variant (none / 0)
Anyway the first thing you can figure out is how fast the stuff spreads so plots like this probably aren't complete ass pulls.

But anything about severity is stage two:

Wouldn't want to make the Dow cry by closing airports.

by generic on Sun Dec 5th, 2021 at 06:37:18 PM EST
[ Parent ]
Re: Latest Data Omicron Variant (none / 0)

UK's progress on Covid now squandered, warns top scientist

The emergence of the Omicron variant shows that the world is "closer to the start of the pandemic than the end", one of Britain's most senior scientific figures has warned, as he lamented a lack of political leadership over Covid.

'Sapere aude'

by Oui (Oui) on Sun Dec 5th, 2021 at 06:37:29 PM EST
Re: Latest Data Omicron Variant (none / 0)


'Sapere aude'
by Oui (Oui) on Sun Dec 5th, 2021 at 06:38:22 PM EST
[ Parent ]
Long Covid After Mild Covid-19 Symptoms (none / 0)


'Sapere aude'
by Oui (Oui) on Sun Dec 5th, 2021 at 06:39:21 PM EST
[ Parent ]
Re: Latest Data Omicron Variant (none / 0)


'Sapere aude'
by Oui (Oui) on Sun Dec 5th, 2021 at 09:02:33 PM EST
Re: Latest Data Omicron Variant (none / 1)


'Sapere aude'
by Oui (Oui) on Sun Dec 5th, 2021 at 09:03:22 PM EST
Re: Latest Data Omicron Variant (none / 0)


'Sapere aude'
by Oui (Oui) on Sun Dec 5th, 2021 at 09:04:36 PM EST
Re: Latest Data Omicron Variant (none / 0)


'Sapere aude'
by Oui (Oui) on Sun Dec 5th, 2021 at 09:05:31 PM EST
Re: Latest Data Omicron Variant (none / 0)


'Sapere aude'
by Oui (Oui) on Mon Dec 6th, 2021 at 10:02:20 AM EST
Re: Latest Data Omicron Variant (none / 0)
wut: "'I'm essentially patient zero,' McGinn told the New York Times."
by Cat on Mon Dec 6th, 2021 at 07:22:31 PM EST
Drop 30 pts from your IQ (none / 0)

Just $4.99/mo from your wallet.
by Cat on Mon Dec 6th, 2021 at 10:17:37 PM EST
Scientists Find 'Stealth' Version of Omicron (none / 0)

Omicron Covid variant is 'already everywhere', WHO says

'Sapere aude'

by Oui (Oui) on Tue Dec 7th, 2021 at 07:18:45 PM EST
[INCONTINENCE ALERT] (none / 0)
by Cat on Wed Dec 8th, 2021 at 07:32:36 PM EST
[ Parent ]
Still Any Doubt Vaccination Makes A Difference? (none / 0)


'Sapere aude'
by Oui (Oui) on Wed Dec 8th, 2021 at 10:15:32 PM EST
Little late in this caper (none / 0)
for experts to be "building a picture" of the human immune (possibly lymphatic) system, immune and autoimmune responses out of just 4 cells, ain't it?
by Cat on Thu Dec 9th, 2021 at 04:46:40 AM EST
Re: Little late in this caper (none / 0)
No idea what that study is supposed to be, but some headline writers seem to have issues with the concept of error bars.
by generic on Thu Dec 9th, 2021 at 07:56:00 AM EST
[ Parent ]
Re: Little late in this caper (none / 1)
Also there's this T-cell guy who's been warning about reliance on T-cells since this started.
by generic on Thu Dec 9th, 2021 at 08:18:10 AM EST
[ Parent ]
Re: Little late in this caper (none / 0)
I've idly been evaluating the immune deficiency AKA immunocompromised AKA immunosuppressed AKA autoimmunity leitmotif in First World "What We Know" industry propaganda since CLINICIANS diagnosed MS in me body 24 years ago--without benefit of genomic sequencing, pathological certainty, or Big Data mining correlative inferences d/b/a "biostatistics", incidentally.

Within the first 5 years of consultation with experts and armed with a rudimentary, secondary school education in biology, chemistry, and logic, I arrived at a conclusion, or plausible threshold, to my own risk management of malpractice by differential diagnoses: Apart from radical and cosmetic surgery and routine  mechanical recovery (bone-setting and "high-risk" organ replacement), moderne medical canon is a massive collection of misplaced precision populating descriptive speculations (primary research d/b/a "peer-reviewed" publications of abstruse and unreproducible experiments with eugenically mass-produced mice populations or eugenically mass-produced human stem cells) that has not advanced prescriptive (applied research) praxis in quite a number of "knowledge domains"--be that hematology, endocrinology, neurology, cardiology, neurology, pulmonology, or more exotic, discrete organizational divisions of uhhh sociology d/b/a abnormal health professions like epidemiologists, the accountants of defective electronic public health records.  

Accordingly, pharmacology dispensed to date is not well understood. Experts licensed to prescribe "therapeutic" formulae, approved for consumption by proprietors of government buildings, rarely encounter much less acknowledge the clinical consequences of their "bioethics" (duly noted by dearly departed Dr. MarketTrustee, my Robert). Much of analog isolated compounds, or mRNA classified, chemistry, is palliative and transitory in their effects d/b/a "disease modulating" chemistry AKA synthetic catalytic conversions expected to replace adverse chemical interactions and "normalized" homeostasis, which is not well understood either. IOW, complex interactions expressed by an "essentialized" schema of What we know about elements associated with regulation of "immune system" DNA organisms that metabolize RNA products.

atm, I hesitate to post an entry here describing my own experience reporting a confounding Rx reaction to combined "disease modulating" Rx1 and Rx2, because I've been advised by Drug 2 manufacturer's agent pharmacists and "nurse educators" as well my prescribing physician that no such ADR and no differential dosage "end-points"  have been published, so; more important, the  zeitgeist here seems to me not amenable to interrogation of units of measurement employed by experts to evaluate any pharmaceutical cost and benefit other than prescribed ineffectual SARS-CoV-2 retroviral agents d/b/a "vaccine hesitancy" and atavistic right-wing ideologues.

by Cat on Thu Dec 9th, 2021 at 05:14:06 PM EST
[ Parent ]
Re: Little late in this caper (none / 0)
under the radar
by Cat on Fri Dec 10th, 2021 at 07:10:08 PM EST
[ Parent ]
Re: Little late in this caper (none / 0)
uh oh.
FDA release of Pfizer-BioNTech report, "5.3.6 CUMULATIVE ANALYSIS OF POST-AUTHORIZATION ADVERSE EVENT REPORTS OF PF-07302048 (BNT162B2) RECEIVED THROUGH 28-FEB-2021," is touring the innerboobs.

Public Health and Medical Professionals for Transparency (phmpt.org) which appears to have established a public repository for FIOA-cleared receipts of FDA embargoed safety reports, 38 pp

with, ahem, voluminous supporting documents such as aggregate COVID-19 Countermeasure Claims compiled by the US HRSA a/o 1 Oct 2021, submitted to the Nevada Board of Health by an illegible signature, 359 pp

by Cat on Mon Dec 13th, 2021 at 05:17:57 PM EST
[ Parent ]
Covid Vaccination Truths and Untruths (none / 0)
COVID infections may give more potent immunity than vaccines - but that doesn't mean you should try to catch it

Infected, Vaccinated, or Both: How Protected Am I From COVID?

Are Antibodies Different After Infection Compared to Vaccination?

Yes. And researchers don't yet understand what these differences mean.

It seems to come down to a question of quality versus quantity. Vaccines seem to produce higher peak antibody levels than natural infections do. But these antibodies are highly specialized, able to recognize only the parts of the virus they were designed to target.

"The mRNA vaccine directs all the immune responses to the single spike protein," says Alice Cho, PhD, who is studying the differences in vaccine and infection-created immunity at The Rockefeller University in New York. "There's a lot more to respond to with a virus than there is in a vaccine."

During an infection, the immune system learns to recognize and grab onto many parts of the virus, not just its spike.

The job of remembering the various pieces and parts of a foreign invader, so that it can be quickly recognized and disarmed should it ever return, falls to immune cells called memory B cells.

Memory B cells, in turn, make plasma cells that then crank out antibodies that are custom tailored to attach to their targets.



'Sapere aude'
by Oui (Oui) on Thu Dec 9th, 2021 at 11:24:10 AM EST
[ Parent ]
Get Shot (none / 1)
Of the ~50.5 million US cases only ~180,000 were vaccinated or 0.004%.  

33% to "more than half" of Covid patients - research is on-going - are Long Covid cases, those that the patient is still suffering the effects of the disease as much as 6 months after being "cured" (sic.)  Lingering, potentially life-long, after affects of Covid-19 include heart, lung, liver, brain, and kidney damage.  

Not getting vaccinated is stupid


She believed in nothing; only her skepticism kept her from being an atheist. -- Jean-Paul Sartre

by ATinNM on Thu Dec 9th, 2021 at 03:50:19 PM EST
[ Parent ]
Re: conflicts of ACE interests (none / 0)
Dambha-Miller et al., "Currently prescribed drugs in the UK that could upregulate or downregulate ACE2 in COVID-19 disease: a systematic review," 19 May (print 4 Aug 2020)
We screened 3360 titles and included 112 studies with 21 different drug classes identified as influencing ACE2 activity. Ten studies were in humans and one hundred and two were in animal models. None examined ACE2 in human lungs.
[...]
Previous studies suggest that dysregulation of ACE2 activity in the lungs could promote early neutrophil infiltration and subsequent uncontrolled activation of the RAS.8 In mice models, acute lung injury was observed in response to SARS-CoV-1 spike protein, so it is plausible that similar responses will be observed with SARS-CoV-2.9 This is particularly problematic in organs containing high ACE2 such as the lungs as it may contribute to cytokine release syndrome (cytokine storm) and the subsequent respiratory failure that has been observed in those who have died from the disease.7 Many prescribed drugs in common use are known to mediate effects through the RAS pathway. Over 45 million of these prescriptions were issued in the UK last year alone, and of these, 15 million were for ACE inhibitors (ACE-I) and angiotensin receptor blockers (ARBs). Acting through the RAS pathway, these drugs may impact ACE2 regulation but their role in the COVID-19 pandemic is not clear. Given the number of people that are potentially on these drugs, it has caused substantial public concern and clinical uncertainty about continuation or cessation of prescribed medications during the pandemic.
Fang et al.,"Are patients with hypertension and diabetes mellitus at increased risk for COVID-19 infection", Lancet correspondence, 11 Mar 2020 (print 18 May 2020)
If this hypothesis were to be confirmed, it could lead to a conflict regarding treatment because ACE2 reduces inflammation and has been suggested as a potential new therapy for inflammatory lung diseases, cancer, diabetes, and hypertension
[...]
We suggest that patients with cardiac diseases, hypertension, or diabetes, who are treated with ACE2-increasing drugs, are at higher risk for severe COVID-19 infection and, therefore, should be monitored for ACE2-modulating medications, such as ACE inhibitors or ARBs
adalimumab indications
B cells and B lymphocyte (TNF blockers)

archived sick care jobs saved or created!, commonly prescribed immune-suppressing mRNA medications not limited to ACE-inhibitors or ARBs

by Cat on Thu Dec 9th, 2021 at 05:47:12 PM EST
[ Parent ]
SARS "spike protein" ACE inhibitors (none / 0)
Mayo, common ACE inhibtors

Mayo, common Angiotnsin 2 receptor blockers (ABRs) a/k/a angiotensin II inhibitors

Age is not "the marker" of adverse outcome of COVID-19 disease.

ACE I and ACE2 represent elemental catalysts in every human cell regardless of age.

Comorbidity d/b/a degenerative diseases, or "pre-existing conditions", is the marker-concerning secondary conditions derived from a smorgasbord of mRNA drugs d/b/a "disease modifying" therapies, or "biologics," prescribed sales staff to disrupt immune system processes and hormonal regulation associated with this one enzyme modified by SARS RNA transcription within cells.

Academic controversy (notably unsupported by trial results involving human subjects captured by commonly prescribed ACE-modifying reactions) have acknowledged, pharmacology can neither control nor predict how those (ACE-receptor) drugs intercept, counter-indicate, or interdict dominant SARS-CoV-2 "vaccines" designed to bind this one, specific receptor region...

without regard to cascading adverse reactions (documented pathology) resulting in hospitalization, morbidity, and predictable death.

AFICT, the controversial T- and B-cell leucocyte "memory" power, arising from FAILED HIV/AID cocktail marketing confirms one fact: mRNA designers have no idea what they're dealing with. They can't even express  rational hypotheses pursuant to predictable viral "neutralization" by "cocktail" prescription.

by Cat on Thu Dec 9th, 2021 at 06:36:54 PM EST
[ Parent ]
Still seems bad (none / 1)
by generic on Thu Dec 9th, 2021 at 10:36:17 PM EST
single point of pharma mRNA engineered FAILURE, (4.00 / 2)
the exquisite cell ACE "receptor", backed by the full faith and credit of FDA, EMA guaranteed purchase and patented "vaccine" production

López-Otín and Judith S. Bond, "Proteases: Multifunctional Enzymes in Life and Disease" (2008)

Thus, proteases regulate the fate, localization, and activity of many proteins, modulate protein-protein interactions, create new bioactive molecules, contribute to the processing of cellular information, and generate, transduce, and amplify molecular signals. As a direct result of these multiple actions, proteases influence DNA replication and transcription, cell proliferation and differentiation, tissue morphogenesis and remodeling, heat shock and unfolded protein responses, angiogenesis, neurogenesis, ovulation, fertilization, wound repair, stem cell mobilization, hemostasis, blood coagulation, inflammation, immunity, autophagy, senescence, necrosis, and apoptosis.
[...]
In terms of specificity, diversity is also a common rule. Thus, some proteases exhibit an exquisite specificity toward a unique peptide bond of a single protein (e.g. angiotensin-converting enzyme); however, most proteases are relatively nonspecific for substrates, and some are overtly promiscuous and target multiple substrates in an indiscriminate manner (e.g. proteinase K). Proteases also follow different strategies to establish their appropriate location in the cellular geography and, in most cases, operate in the context of complex networks comprising distinct proteases, substrates, cofactors, inhibitors, adaptors, receptors, and binding proteins, which provide an additional level of interest but also complexity to the study of proteolytic enzymes.
archived 3CL protease inhibitor (A/V molecular bio primer), feat. "wide spectrum" ivermectin therapeutic effect, a WHO designated "ESSENTIAL" medicine and NOBEL prize award (2015); nsp14 specimen mutations with characteristics of scientific racism; select FDA licensed antiretroviral "cocktails", feat. 6 patented, brand-name protease inhibitors
by Cat on Fri Dec 10th, 2021 at 06:28:35 PM EST
[ Parent ]
Re: single point of pharma mRNA engineered FAILURE (none / 0)
But Dr. Jill Biden told me the air smells so much sweeter without the masks?

Pretty sure the Ivermectin stuff is still nonsense, though. Unless you have worms when they shoot you full of steroids, then it should help.

by generic on Fri Dec 10th, 2021 at 07:39:30 PM EST
[ Parent ]
Re: single point of pharma (none / 0)
COVID-19 Vaccines and People with HIV - FAQ

'Sapere aude'
by Oui (Oui) on Fri Dec 10th, 2021 at 08:39:37 PM EST
[ Parent ]
Origin of Omicron Mutation (none / 0)


'Sapere aude'
by Oui (Oui) on Sat Dec 11th, 2021 at 07:02:03 PM EST
Covid Booster Shot and Protection Omicron Variant (none / 0)


'Sapere aude'
by Oui (Oui) on Sat Dec 11th, 2021 at 07:04:31 PM EST
Covid Booster Shot and Protection Omicron Variant (none / 0)


'Sapere aude'
by Oui (Oui) on Sat Dec 11th, 2021 at 07:05:34 PM EST
[ Parent ]
Shot and Protection contradictions (none / 0)
hmm, the right hand (JP) doesn't know what the left hand (Guardian) is signaling.
by Cat on Mon Dec 13th, 2021 at 02:26:55 PM EST
[ Parent ]
Exponential Surge English Omicron Cases (none / 0)


'Sapere aude'
by Oui (Oui) on Sun Dec 12th, 2021 at 05:51:45 PM EST
Re: Exponential Surge English Omicron Cases (none / 0)


'Sapere aude'
by Oui (Oui) on Sun Dec 12th, 2021 at 05:52:48 PM EST
[ Parent ]
Re: Exponential Surge English Omicron Cases (none / 0)

3,137 Omicron cases have now been reported in the UK

'Sapere aude'

by Oui (Oui) on Sun Dec 12th, 2021 at 07:33:29 PM EST
[ Parent ]
Re: Latest Data Omicron Variant (none / 0)


'Sapere aude'
by Oui (Oui) on Sun Dec 12th, 2021 at 05:53:39 PM EST
Re: Latest Data Omicron Variant (none / 0)
The relatively few number of Omicron patients compared to the total number vaccinated gives a 'Hardy-har-har' Confidence factor.  It may turn out Omicron is the ubermensch of SARS-CoV-2.  It may turn out to be a damp squib wrt the vaccinated.

We don't know.

Indications the unvax'ed are going to be dropping like flies. ? Possibly/Maybe?  We don't know that either as of Dec 13, 2021


She believed in nothing; only her skepticism kept her from being an atheist. -- Jean-Paul Sartre

by ATinNM on Mon Dec 13th, 2021 at 08:43:43 PM EST
[ Parent ]
Japan breaks ranks (none / 1)
Alert: Japan Places Myocarditis Warning on 'Vaccines' - Requires Informed Consent
Japan's Ministry of Health of health website encourages citizens to receive the "vaccine"; however, they stress it is not mandatory.
Although we encourage all citizens to receive the COVID-19 vaccination, it is not compulsory or mandatory. Vaccination will be given only with the consent of the person to be vaccinated after the information provided
In addition, the government recommends those who are considering taking the shot carefully consider both its effectiveness and side effects.
Please get vaccinated of your own decision, understanding both the effectiveness in preventing infectious diseases and the risk of side effects. No vaccination will be given without consent.
Furthermore, they stress ...
Please do not force anyone in your workplace or those who around youThe government even links to a "Human Rights Advice," including instructions for handling any complaints if individuals face "vaccine" discrimination at work. to be vaccinated, and do not discriminate against those who have not been vaccinated.
Blinken threat assessment story developing ...
by Cat on Mon Dec 13th, 2021 at 02:38:59 PM EST
Re: Japan breaks ranks (none / 0)
Well their car industry is collapsing as a result of being so far behind the curve on EVs. Maybe Japan's century is over also.
by asdf on Tue Dec 14th, 2021 at 12:42:11 AM EST
[ Parent ]
Re: Japan breaks ranks (none / 0)
Not sure what "Japan's century" means to you apart from automotive industry competition, starting in the 70s, but I think we can agree, sales growth no longer depends on US market entry. Japanese brands produce as many vehicles as USA, in as many markets as USA, and leverages JV with both Euro, US, and Chinese manufacturers. Their share is wide and deep, especially in the global south.

OTOH, the US new car market has been collapsing (into the secondary market) for two decades, because of escalating MSRP (offset by manufacturers' finance ops) is beyond the reach of median HH income, where value, inventory, and preference for shitty mpg ICE vehicles converge. Moreover, average trade-in cycle ("lifespan") which ranged 4-7 years at the turn of the century is now around 12 years.

Doom of the day is strictly for American consumption

by Cat on Tue Dec 14th, 2021 at 07:49:05 PM EST
[ Parent ]
Re: Japan breaks ranks (none / 0)
as I was saying ....
by Cat on Tue Dec 14th, 2021 at 10:51:25 PM EST
[ Parent ]
Re: Japan breaks ranks (none / 0)
Well, I was thinking "Japanese century" in the sense that they modernized to the point of competitiveness with Russia early in the century, then the US midway, then globally after WW2.

As far as cars go, they currently sell a lot. But their EV situation is pretty bad. Maybe they will catch up with South Korea, China, the US, and the EU, but they had better get going.

by asdf on Sat Dec 18th, 2021 at 01:25:14 AM EST
[ Parent ]
Re: Japan breaks ranks (none / 1)
They kinda took the lead in EV car market with Leafs and Priuses, but mid 201os the whole nation started this "hydrogen society" -thing, and car makers followed the trend. So their focus is mostly on hydrogen cars now, an area where they, I think, clearly lead at the moment.
by pelgus on Sat Dec 18th, 2021 at 10:54:05 AM EST
[ Parent ]
Re: Latest Data Omicron Variant (none / 1)
BoJo sez, At least one person in UK has died with Omicron
Pressed several times about whether a "plan C" of further restrictions would be necessary, Johnson said: "Throughout the pandemic I've been at great pains to stress to the public that we have to watch where the pandemic is going and we take whatever steps are necessary to protect public health.

"We think the steps that we are taking - so plan B, combined with a hugely ambitious acceleration of the booster campaign, bringing it forward by a month so we offer a booster to every adult by the end of the year - we think that's the right approach."

'plan C'
No 10 said about 750 troops have been mobilised to support the NHS with its vaccination programme, including medics, strategists and 50 military planning experts. Johnson's spokesman also insisted that people should have no worries about cancer appointments being cancelled for the vaccination programme.

WaPoo sez, Johnson says 'at least one' person has died from omicron
archived world leaders in repatriations, contact, tracing, and testing Fri Jan 24th, 2020, Mon Feb 3rd, 2020

by Cat on Mon Dec 13th, 2021 at 03:40:14 PM EST
British Data Omicron Variant (none / 0)
Omicron could cause tens of thousands of deaths in England, study says
The Omicron variant could cause tens of thousands of deaths in England by the end of April if additional virus restrictions are not imposed, new modelling suggests.
less than 510,000
Researchers said the new variant, which is expected to be more transmissible, could cause 24,000 deaths by 30 April 2022 in the most optimistic scenario and nearly 75,000 deaths in the most pessimistic scenario.
NHS Website Crashes Over Huge Demand for COVID-19[sic] Booster Jabs After 1st Omicron Death Confirmed
by Cat on Mon Dec 13th, 2021 at 06:41:33 PM EST
[ Parent ]
Re: British Data Omicron Variant (none / 0)
Mortality rate will be quite low ... the unvaccinated will be bothered by the infection and will be independent on age, from the very young >2 years. In the Netherlands once again the nursing homes are left unprotected and the government reaction to adding booster jabs and preparation for Omicron variant is running weeks late. Thousands extra have already died since the Summer, these deaths will not be  registered as Covid deaths.

More worrisome are the long term effects of both the Covid-19 illness and the vaccines. Two children died while participating in sports ... one from a bleeding on the brain an another from heart failure 😞

In a  parochial primary school in England two children died unexpectedly. My fear is this will be more common as both the illness and vaccine cause complications on a small scale, but won't go unnoticed.

'Sapere aude'

by Oui (Oui) on Mon Dec 13th, 2021 at 07:35:44 PM EST
[ Parent ]
Re: British Data Omicron Variant (none / 0)
Mortality rate will be quite low
Why? We did get full court press around the idea that Omicron was "mild" after the initial panic, but there was clearly no data to back this up. The typical way from the first cough to the mortuary is about 20 days. There are two obvious effects that would make a new variant appear more mild at first: If a lot of people who would have shrugged off an infection in earlier versions now get mild symptoms you change the denominator. Yes, a smaller ratio of people get severe illness, but the overall number of people who get severely ill or die could still be larger compared to earlier variants.
Two, the people who spread the virus over the whole population are usually not the most vulnerable and only a few iterations after the first outbreak will you see a large number of vulnerable people get into contact with the virus.

They did the exact same bullshit when Delta broke.

by generic on Mon Dec 13th, 2021 at 07:55:34 PM EST
[ Parent ]
Re: British Big Data (none / 0)
"larger than" is a pretty high hurdle to clear unless NHS services and treatment plans have significantly deteriorated since ... the summer delta "surge."

I stopped following the "surge" of NHS service and equipment complaints (illustrated with corridor triage gurneys) last spring, because I gave up trying to decode Guardian headlines.

Have hospital capacity and clinical prognosis improved with treatment protocol over the period? I hesitate to assume that they have, simply because the presses aren't bragging about it.

by Cat on Mon Dec 13th, 2021 at 09:29:02 PM EST
[ Parent ]
Re: British Data Omicron Variant (none / 0)
From the earliest I have written about the Delta variant, it was clear this wasn't a mild version but more contagious and troublesome.

Reproduction factor 2.0 - highest since Feb. 2020 | July 13, 2021 |

'Sapere aude'

by Oui (Oui) on Mon Dec 13th, 2021 at 10:32:16 PM EST
[ Parent ]
Re: British Data Omicron Variant (none / 1)
It's been known for some time asymptomatic cases can nevertheless cause serious heart damage leading to the little tykes dropping dead from myocardial infarction.

She believed in nothing; only her skepticism kept her from being an atheist. -- Jean-Paul Sartre
by ATinNM on Mon Dec 13th, 2021 at 08:50:29 PM EST
[ Parent ]
Re: Latest Data Omicron Variant (none / 0)

Three charts show South Africa's Covid crisis as omicron takes hold | CNBC |

'Sapere aude'

by Oui (Oui) on Mon Dec 13th, 2021 at 11:06:49 PM EST
Re: Latest Data Omicron Variant (none / 0)


'Sapere aude'
by Oui (Oui) on Mon Dec 13th, 2021 at 11:07:45 PM EST
Report from #gauteng South Africa (none / 0)


'Sapere aude'
by Oui (Oui) on Mon Dec 13th, 2021 at 11:09:42 PM EST
Re: Report from #gauteng South Africa (none / 0)
Inflection point May have passed ...



'Sapere aude'
by Oui (Oui) on Mon Dec 13th, 2021 at 11:10:37 PM EST
[ Parent ]
South Africa Latest On Omicron (none / 0)
South Africa fatality rate Omicron variant from 3% down to 0.5%



'Sapere aude'
by Oui (Oui) on Tue Dec 14th, 2021 at 08:44:01 AM EST
Re: South Africa Latest On Omicron (none / 0)
Julia Hartley-Brewer is a notorious far-right loon and has never been right about anything.

Please don't quote her on ET.

by ThatBritGuy (thatbritguy (at) googlemail.com) on Tue Dec 14th, 2021 at 10:36:27 AM EST
[ Parent ]
Re: South Africa Latest On Omicron (none / 0)
Of course it was about Dr Angelique Coetzee on the ground in Pretoria. She might be more outspoken as a politician than doctor, however all data from South Africa indicate Omricon is milder in comparison to the Delta variant.

'Sapere aude'
by Oui (Oui) on Tue Dec 14th, 2021 at 11:26:43 AM EST
[ Parent ]
Re: South Africa Latest On Omicron (none / 1)
Calculating a CFR for a variant that has only been around for one mean time to death is certainly something.

Just because it came across my Twitter:

I would expect we get some indication about severity this week or the next. Letting it run wild before we have anything is pure lunacy.

by generic on Tue Dec 14th, 2021 at 12:39:35 PM EST
[ Parent ]
Re: South Africa Latest On Omicron (none / 1)
Many virologists write about their experiences. Due to early vaccinations and protection wearing down after six months, Israel, Hungary, the UK and Belgium started the third and booster shot on time. The Netherlands in a two year long laissez-faire policy started nearly three months later than Belgium and at a very slow pace. Appears the virus mutants travel faster across the globe than data and knowledge for politicians and even scientists. Seeing is believing.

Get your booster shot and be safe. I'll get mine next week.

In the meantime do not lower your guard!



'Sapere aude'
by Oui (Oui) on Tue Dec 14th, 2021 at 01:56:11 PM EST
[ Parent ]
Re: South Africa Latest On Omicron (none / 1)
I've got mine as soon as Austria opened up for all age groups about three weeks ago. I've also been wearing a FFP2 equivalent in nearly all situations I was around people not in my immediate household and using a rapid test before going under people.
Talking about masks, I can recommend the 3M aura FFP2s. No glass fogging and they don't get vastly more uncomfortable after six hours of use.
Still would prefer if it wouldn't come down to personal paranoia.
by generic on Tue Dec 14th, 2021 at 03:04:05 PM EST
[ Parent ]
Re: South Africa Latest On Omicron (4.00 / 2)
Short of biolab-grade PPE, the Auras seem to be the gold standard. I use the Aura FFP3s if I'm going to be spending time among the public. A lot of FFP3s are really FFP2s at best, which are fine for relatively short exposure but not for a full working day.

Lateral/rapid tests have a lag of a day or so during which you can be infectious but the test isn't sensitive enough to show it. The best option continues to be masking and distancing. And full avoidance if possible.

by ThatBritGuy (thatbritguy (at) googlemail.com) on Wed Dec 15th, 2021 at 09:40:34 AM EST
[ Parent ]
Re: South Africa Latest On Omicron (none / 0)
I'm not sure that FFP3s are strictly necessary. As far as I'm aware they use FFP2s in hospitals down here, though hospitals of course have much better ventilation than you're likely to encounter anywhere else. Nonetheless, I'm probably also going to switch to the FFP3 version once I'm through my current reserves.
by generic on Wed Dec 15th, 2021 at 10:44:13 AM EST
[ Parent ]
Re: South Africa Latest On Omicron (none / 0)


'Sapere aude'
by Oui (Oui) on Tue Dec 14th, 2021 at 02:00:01 PM EST
[ Parent ]
Re: Latest Data Omicron Variant (none / 0)

Waning COVID super-immunity raises questions about Omicron | Nature |

'Sapere aude'

by Oui (Oui) on Tue Dec 14th, 2021 at 02:19:11 PM EST
Re: Latest Data Omicron Variant (none / 1)
South African doctors see signs omicron is milder than delta | ABC News / AP News |

According to South Africa's National Institute for Communicable Diseases:

  • Only about 30% of those hospitalized with COVID-19 in recent weeks have been seriously ill, less than half the rate as during the first weeks of previous pandemic waves.
  • Average hospital stays for COVID-19 have been shorter this time - about 2.8 days compared to eight days.
  • Just 3% of patients hospitalized recently with COVID-19 have died, versus about 20% in the country's earlier outbreaks.
"At the moment, virtually everything points toward it being milder disease," Willem Hanekom, director of the Africa Health Research Institute said, citing the national institute's figures and other reports. "It's early days, and we need to get the final data. Often hospitalizations and deaths happen later, and we are only two weeks into this wave."



'Sapere aude'
by Oui (Oui) on Tue Dec 14th, 2021 at 04:52:48 PM EST
Do I Need To Get Vaccinated? (none / 0)


'Sapere aude'
by Oui (Oui) on Wed Dec 15th, 2021 at 10:20:34 AM EST
One Question Answered (none / 1)
One question is answered: how contagious is Omnicron?

Dr. Tedros: "Omicron is spreading at a rate we have not seen with any previous variant."

Omicron is rising rapidly in the US--3% of cases nationally, 13% in NY and NJ

Currently, the US is seeing around 120,000 new COVID cases per day, a 49 percent increase over two weeks ago. The country is averaging 66,500 hospitalizations a day, which is a 22 percent increase. For now, nearly all of the cases and hospitalizations are due to delta, but that will likely change quickly with omicron.

We should have a good idea of its virulence in about 10 to 14 days.

She believed in nothing; only her skepticism kept her from being an atheist. -- Jean-Paul Sartre

by ATinNM on Wed Dec 15th, 2021 at 04:51:20 PM EST
Re: One Question Answered (none / 1)
From the link:

"I need to be very clear," Dr. Tedros said. "Vaccines alone will not get any country out of this crisis... It's not vaccines instead of masks. It's not vaccines instead of distancing. It's not vaccines instead of ventilation or hand hygiene. Do it all. Do it consistently. Do it well."

If the world had followed China's example instead of the US' we'd have this thing under control.

She believed in nothing; only her skepticism kept her from being an atheist. -- Jean-Paul Sartre

by ATinNM on Wed Dec 15th, 2021 at 04:54:12 PM EST
[ Parent ]
10-14 days (none / 1)
US faces a DOUBLE coronavirus SURGE as omicron advances
"Our DELTA surge is ongoing and, in fact, accelerating. And on top of that, we're going to add an OMICRON surge," said Dr. Jacob Lemieux, who monitors variants for a research collaboration led by Harvard Medical School
[...]
Most likely, he and other experts said at a press briefing Tuesday, an omicron surge is already under way in the United States, with the latest mutant coronavirus outpacing the nation's ability to track it
with "omicron specific" at-home test kits
by Cat on Wed Dec 15th, 2021 at 07:13:39 PM EST
[ Parent ]
Protection for the Corona virus ... (none / 1)
If the Alpha or Beta or Delta variant hasn't already illustrated the status of a nation and it's war against SARS Cov-2, the Omicron certainly will two years after its birth in China.

The Omnicron virus loves anti-vaxxers, red states and the very young persons across the USA.

Natural immunity after illness plus a few jabs of vaccines makes the spread of invections more difficult. Strict basic rules too are important ... humans are tired, the virus is reinvigorated ... we'll see in a few weeks or months who is winning.

The goal of herd immunity is a farce, the virus is here to stay.

The UK at it's best in the vaccination program has followed Tory preference to save the economy and don't look "stupid" to ban drinks in pubs, the English way.

UK the numbers 78,610 new cases today.

'Sapere aude'

by Oui (Oui) on Wed Dec 15th, 2021 at 08:30:44 PM EST
[ Parent ]
Re: Protection for the Corona virus ... (none / 1)

His lobby killed him ...

GOP State Senator Doug Ericksen confirms to @KIRORadio he's in rough shape with Covid. He says he's currently in El Salvador & unable to leave the country. Monoclonal antibodies not available there. He's asking House and Senate R's to find a way to get those meds to him

Why Is a Washington State Senator Lobbying for Cambodia?

'Sapere aude'

by Oui (Oui) on Sun Dec 19th, 2021 at 03:46:33 PM EST
[ Parent ]
Re: 10-14 days to live (none / 0)
CIVIL RIGHTS ICON of a US American ERA
by Cat on Sun Dec 19th, 2021 at 11:55:44 PM EST
[ Parent ]
Re: Latest Omicron Variant (none / 0)
Fauci: No need for modified vaccine for [DEADLY, 70X MORE INFECTIOUS, "EVADING"] omicron at this point
Early studies have shown much stronger protection after three doses, though. Early data from the UK showed effectiveness against infection with three [mRNA] doses rose back to 75 percent, from about 30 percent after two doses.
by Cat on Thu Dec 16th, 2021 at 12:33:14 AM EST
You Can't Hide, Covid Will Smoke You Out (none / 0)

American scientist contrasts Taiwan's coronavirus cases with Florida's | Taiwan News |

Rightly so, each Florida Covid-19 death could be traced to DeSantis policy. Can't we just publish the Florida war with the DeSantis mutant? Honor where honor is due. Normally one would have to go to war to claim this number of civilian deaths ...

'Sapere aude'

by Oui (Oui) on Thu Dec 16th, 2021 at 04:07:15 PM EST
Enough Surgical Masks for A Century (none / 0)
Health ministry faces having to destroy millions of unused surgical masks

The Dutch government will have to destroy much of its stock of 848 million face masks because it is unable to give them away during a pandemic, the Volkskrant reported on Tuesday.

A recent audit of PPE gear found that the Netherlands has enough supplies of surgical masks to keep hospitals stocked for more a century and 50 years' worth of FFP2 masks.



'Sapere aude'
by Oui (Oui) on Thu Dec 16th, 2021 at 07:47:01 PM EST
The Dutch and Intelligent Lockdown (none / 0)
Bada$$ stupidity ...

Price of face masks plummets following Dutch government fire sale

Fleur Bakker, of the Mondmaskerfabriek, said her company had been offered boxes of masks from Lithuania for between €1.25 and €2 for a box of 50 masks via a Dutch intermediary.

Further enquiries revealed that the masks were the same ones the Lithuanian firm had bought from the government's procurement agency LCH for around €0.64 per box last year.

'Sywert van Lienden earned a lot from the import of face masks'

Making of three multi-millionaires over night. One scandal after another ... the "new" Rutte cabinet should not survive it's maiden debate ... more of the same in old wine sacks.

'Sapere aude'

by Oui (Oui) on Thu Dec 16th, 2021 at 07:49:42 PM EST
[ Parent ]
Re: Latest Data Omicron Variant (none / 0)
Netherlands remains dark red on EU Covid map for fifth week

Dutch Health Ministry: spending hundreds of millions on PPE as the elderly died from lack of protection ...

Enough Surgical Masks for A Century

'Sapere aude'

by Oui (Oui) on Thu Dec 16th, 2021 at 08:11:21 PM EST
Re: Latest USAMRIID Data (none / 1)
Learning from Covid, researchers prep universal vaccine for next coronavirus outbreak, 2021
In November, the Walter Reed [Army Institute of Research] vaccine -- which would provide immunity against several different coronaviruses -- completed phase 1 human trials [n=29 after exclusions], marking an important step forward. Unlike the mRNA vaccines developed at warp speed to combat Covid-19, universal coronavirus vaccines remain several years away from distribution.
Fauci pushes for universal coronavirus vaccine, 2021

reference
C-SPAN | Universal Flu Vaccine Milkin Institute panel, 2019
feat. Fauci
Warren offers infectious-disease plan amid China outbreak 2020
"including a universal immunization against the flu ... to increase NIH funding by $100 billion"

archived living lab Thu Jan 30th, 2020

by Cat on Fri Dec 17th, 2021 at 11:31:17 PM EST
Re: Latest USAMRIID ebola marketing (none / 1)
Congo declares end [again] to latest Ebola outbreak in the east
Research has shown that the first case from the latest outbreak "likely represented a new flare-up of the 2018-2020 Ebola outbreak due persistence of the virus in the community," WHO said Thursday.

Scientists have previously documented Ebola survivors who inadvertently [?!] infected others long after they had recovered. For example, health officials have warned that the virus can persist in male survivors' semen for more than a year.
[...]
While the 2018-2020 pandemic [sic] marked the first time that vaccines could be given to those at risk, insecurity in rural areas prevented health workers from safely accessing many.

Not contained, new cases: three questions on vaccines and the Ebola outbreak in DRC, 2019
Right now, "ring" vaccination is being used. This entails vaccinating anyone who's been in contact with someone infected with Ebola, as well as all of their contacts. The reasoning behind the method isn't bad per se. But implementing it is time-consuming and challenging (problems with identifying each and every person's individual contacts) and it's not adapted to the insecurity affecting North Kivu.

archived living lab
Sat May 12th, 2018 vaccines,
Tue Jun 4th, 2019 Merk,
Sat Aug 18th, 2018 more vaccines,
Fri Mar 13th, 2020 ring vaccination

by Cat on Sat Dec 18th, 2021 at 12:26:20 AM EST
[ Parent ]
Re: Latest USAMRIID Data UPDATE! (none / 0)
US Army Wraps Preclinical Trials on COVID-19 Vaccine Designed to Combat Variety of Variants
While the SpFN has yet to be tested on the omicron variant, "testing against the variants is ongoing in a ["]neutralization["] assay [FKA serological assay AKA antibody test] in the laboratory [in vitro]," the facility noted. The WRAIR went on to claim that facility scientists "remain encouraged" by early data from preclinical trials, which were published on December 16 in Science Translational Medicine, an interdisciplinary medical journal.
means, motive, opportunity
Researchers are now analyzing data from Phase One of human trials, but no timeline was provided. The WRAIR's protein subunit nanoparticle [FKA CRISPR substitution] vaccine works by presenting a fragment of the SARS-CoV-2 virus to one's immune system to elicit a broad, protective response. The SpFNincludes ALFQ, a vaccine adjuvant that is part of the Army Liposome Formulation (ALF) family[
[..]
According to the facility, the vaccine could potentially be useful on a global scale, as it remains stable at a wide range of temperatures, unlike the Pfizer-BioNTech and Moderna-developed vaccines, which require refrigeration.
[...]
"We need to evaluate it in the real-world setting and try to understand how does the vaccine perform in much larger numbers of individuals who have already been vaccinated with something else initially [...] or already been sick," [Dr. Kayvon Modjarrad] told the outlet in an exclusive interview.

by Cat on Wed Dec 22nd, 2021 at 11:19:40 PM EST
[ Parent ]
Re: Latest Data Omicron Variant (none / 0)
There are over 10,000,000 active Covid cases in the US, the highest since the pandemic began.

There have been 885,499 new cases in the last 7 days.

At the moment there are ~2.8 million news cases of Covid-19 per month.

17% of US citizens are fully vaccinated, meaning fully shot and boosted.

She believed in nothing; only her skepticism kept her from being an atheist. -- Jean-Paul Sartre

by ATinNM on Sat Dec 18th, 2021 at 05:00:29 PM EST
We Don't Do Monday Morning QB (none / 0)
The Dutch were late-later-latest in the EU-26 to start the booster vaccine program ...

Today the ministers and the OMT scientists state they won't look back, but ahead what needs to be done to mitigate the new variant no one had expected ...:taken by surprise ... Mark Rutte and Health Minister De Jong "go by the science" and specifically "monitor neighboring countries."

A very compliant main stream media, especially the nitwits of editorial teams of television channels offer no arguments to defy the caretaker cabinet. No leadership and deficient in taking courageous

One member of the OMT team argued they followed the modeling of cases, hospitalization and ICU occupancy. Science and politicians have been too optimistic and the virus mutations changed their plans. The budget for 2022 was written with the expectation the pandemic would have ended.

The scientist was aware the input for the modeling was based on inputs which were largely assumptions. No one is 100% correct ...

Indeed, the Dutch defying all odds and end at the bottom of the heap. Math, probability and stats is not on everyone's curriculum. Sometimes it appears simple math is lacking in new generations and all needs to be presented in ready to consume conclusions. Critical thinking is not part of Dutch politicians and media.

Netherlands to enter 4-week lockdown from Sunday: Source

From the diaries ...



'Sapere aude'
by Oui (Oui) on Sat Dec 18th, 2021 at 05:17:59 PM EST
Re: We Don't Do Monday Morning QB (none / 1)
Covid: Dutch go into Christmas lockdown over Omicron wave - BBC
The Netherlands has announced a Christmas lockdown amid concerns over the Omicron coronavirus variant.

Non-essential shops, schools, bars, restaurants and other public venues will be closed until at least mid-January. Prime Minister Mark Rutte said the restrictions were "unavoidable".

It marks the strictest rules to have been announced over Omicron so far.

by Bernard (bernard) on Sat Dec 18th, 2021 at 06:38:27 PM EST
[ Parent ]
Re: We Don't Do Monday Morning QB (none / 0)


'Sapere aude'
by Oui (Oui) on Sat Dec 18th, 2021 at 07:53:16 PM EST
[ Parent ]
Re: We Don't Do Monday Morning QB (none / 0)

WRONG! Is still a caretaker cabinet ... new ministers are sought and new cabinet expected in 2nd week January.

'Sapere aude'

by Oui (Oui) on Sat Dec 18th, 2021 at 07:54:13 PM EST
[ Parent ]
Re: We Don't Do Monday Morning QB (none / 0)


'Sapere aude'
by Oui (Oui) on Sat Dec 18th, 2021 at 07:54:53 PM EST
[ Parent ]
Re: We Don't Do Monday Morning QB (none / 0)


'Sapere aude'
by Oui (Oui) on Sat Dec 18th, 2021 at 07:55:54 PM EST
[ Parent ]
Re: We Don't Do Monday Morning QB (none / 0)


'Sapere aude'
by Oui (Oui) on Sat Dec 18th, 2021 at 07:57:30 PM EST
[ Parent ]
Re: We Don't Do Monday Morning QB (none / 1)
"return after the break" to stay at home for another term of Zoom classes, actually
by asdf on Sun Dec 19th, 2021 at 01:45:54 AM EST
[ Parent ]
Re: We Don't Do Monday Morning QB (none / 0)


'Sapere aude'
by Oui (Oui) on Sat Dec 18th, 2021 at 07:59:25 PM EST
[ Parent ]
Re: We Don't Do Monday Morning QB (none / 0)


'Sapere aude'
by Oui (Oui) on Sat Dec 18th, 2021 at 08:00:24 PM EST
[ Parent ]
Re: We Don't Do Monday Morning QB (none / 0)


'Sapere aude'
by Oui (Oui) on Sat Dec 18th, 2021 at 08:02:01 PM EST
[ Parent ]
Re: Latest Data Declaration (none / 1)
Great Barrington Declaration
As infectious disease epidemiologists and public health scientists we have grave concerns about the damaging physical and mental health impacts of the prevailing COVID-19 policies, and recommend an approach we call Focused Protection. [...] As immunity builds in the population, the risk of infection to all - including the vulnerable - falls. We know that all populations will eventually reach herd immunity - i.e.  the point at which the rate of new infections is stable - and that this can be assisted by (but is not dependent upon) a vaccine. Our goal should therefore be to minimize mortality and social harm until we reach herd immunity [!]. The most compassionate approach that balances the risks and benefits of reaching herd immunity, is to allow those who are at minimal risk of death to live their lives normally to build up immunity to the virus through natural infection, while better protecting those who are at highest risk. We call this Focused Protection. ...
by Cat on Sat Dec 18th, 2021 at 09:07:50 PM EST
Rightwing Folly Unnecessary Deaths (none / 0)


'Sapere aude'
by Oui (Oui) on Sun Dec 19th, 2021 at 08:42:40 AM EST
Re: Rightwing Folly Unnecessary Deaths (4.00 / 2)
Hope Japan can keep it up. They're pretty close to eradication.
It's also a show case of what you could have used the vaccinations for if you weren't deep into magical thinking about herd immunity. Basically they were very effective in preventing infection for a (very) few months after finishing the course and Japan started late, but once they started they vaccinated everyone pretty efficiently. I guess being used to wearing masks also helps.
Now if they just could squash the last clusters and implement a comprehensive quarantine requirement before they get a helping of Omicron...
by generic on Sun Dec 19th, 2021 at 10:00:08 AM EST
[ Parent ]
Stricter Rules Travelers from UK (none / 0)


'Sapere aude'
by Oui (Oui) on Sun Dec 19th, 2021 at 02:04:05 PM EST
The Pandemic Experiment of Trial and Error (none / 0)
Number of tests and positivity rates ...

Dutch caretaker cabinet and OMT Team surprised by serie of SARS CoV-2 variants.

Loosening too soon, ahead in Europe with economic recovery and surprising low unemployment ... a matter of priority.

'Sapere aude'

by Oui (Oui) on Sun Dec 19th, 2021 at 05:45:16 PM EST
Re: The Pandemic Experiment of Trial and Error (none / 0)
Covid-19: Stop tracing and quarantining of contacts, says Ministerial Advisory Committee, sampling errors galore
The proportion of people with immunity to Covid-19 (from infection and/or vaccination) has risen substantially, exceeding 60-80% in several serosurveys [measuring of antibody levels against infectious diseases].

"We have learned more about the manner in which Covid-19 is spread, and also now have to contend with variants of concern whose epidemiology differs from that of the ancestral strains of SARS-CoV-2.
[...]
"In addition, among the small proportion of symptomatic cases, testing is far from universal, since patients may not seek testing when their symptoms are mild and when testing would be burdensome and expensive. Furthermore, the SARS-CoV-2 test sensitivity is suboptimal, sometimes leading to false negative results.

"The inability of the current testing strategy to identify the bulk of cases is illustrated by the high SARS-CoV-2 seropositivity rates seen across multiple provinces in serosurveys, implying that only a fraction of cases (perhaps one in 10, or even less) are ever diagnosed."

by Cat on Sun Dec 19th, 2021 at 09:11:16 PM EST
[ Parent ]
Re: The Pandemic throne of lies (none / 0)
HHS forecast shows Omicron stretching U.S. Covid [sic] testing supply.
NB. HHS/CDC interest in SARS-CoV-2 variants and antibodies of concern ended last year in time for Joe's Independence Day (April) and before Fauci's (un)expected delta SURGE (July).
The U.S. is currently recording more than 1.6 million daily Covid-19 tests, according to a tracker maintained by Johns Hopkins University. Many at-home antigen tests are not reported to public health authorities -- meaning millions of results from the increasingly popular [if unavailable] rapid [COVID-19] tests are likely not included in that count.
soooo how does the administration arrive at
estimates that the number of infections driven by the [omicron] is doubling every two days.
oh right. Self-diagnosed "scratchy throat" instead of "sore throat" indicates the omicron pathogen.
by Cat on Sun Dec 19th, 2021 at 11:16:41 PM EST
[ Parent ]
Re: The Pandemic throne of lies (none / 0)
Public health experts and even some lawmakers have warned for months that the U.S. needs a ["]more robust["] testing system, especially with the virus[es] likely to continue circulating well after the pandemic officially[?!] ends
again.
"The thing that's more important than the number of tests is how fast the results come back," [The Rockefeller Foundation's Pandemic Prevention Institute pathogen surveillance director Sam] Scarpino said. "In some ways, it would be more important for us to be doing fewer [COVID-19] tests and getting them back to people faster. We're gonna have to be ready for prioritizing who gets access to those tests."
by Cat on Sun Dec 19th, 2021 at 11:26:30 PM EST
[ Parent ]
Re: The Pandemic throne of lies (none / 0)
Q. When are "estimates in a range" a count?
A. Never.

Q. When is "overcounting" fully- and triple-vaccinated persons as a never- and partially-vaccinated population politically advantageous for FDA clients and democratically elected representatives of the most ignorant, litigious nation on planet?
A. When pharmaceutical prescriptions for escalating "estimates in a range" of moderate and severe COVID-19 cases is demonstrably ineffective.

Vaccine Data Gaps Point to Millions More in U.S. Who Lack Shots

"We don't have any faith in the numbers on the CDC website, and we never refer to them," [James Garrow, a spokesman for the Philadelphia Department of Public Health] said.
[...]
The official U.S. gap between people with just one dose and those who are fully vaccinated -- about 11 percentage points -- far outpaces other nations. The next highest gap discrepancy among G7 nations is the U.K., at 6.7 percentage points, according to the Bloomberg Vaccine Tracker. ... In the European Union, it's just 2.6 percentage points.

State officials say the explanation isn't that Americans are uniquely unlikely to get a second shot but instead that the country's health system, unlike its G-7 peers, is exceptionally fragmented. Each state maintains its own set of data, some have several, and all ["]blend["] their information with data from health providers such as pharmacies and federal programs

by Cat on Mon Dec 20th, 2021 at 03:52:47 AM EST
[ Parent ]
Re: The Pandemic throne of lies (none / 0)
Yeah, the US is probably the most boosted country. Max Titers tends to lose his vax card a lot.
by generic on Mon Dec 20th, 2021 at 07:06:56 AM EST
[ Parent ]
Re: The Pandemic throne of lies (none / 0)
Colorado Democrat tests positive for COVID-19 after trip to to Ukraine
Hours before Crow announced his diagnosis, Sens. Elizabeth Warren (D-Mass.) and Cory Booker (D-N.J.) revealed that they tested positive for COVID-19 breakthrough cases.

Warren said she tested positive on Sunday, noting that she "regularly test[s] for COVID." She said she is experiencing mild symptoms, crediting the vaccine and booster shot for protecting her against serious illness.

pre-alpha, alpha, beta, delta, gamma, lamda, or omicron?
by Cat on Mon Dec 20th, 2021 at 01:59:29 PM EST
[ Parent ]
Re: The Pandemic Experiment of Trial and Error (none / 0)
by Cat on Sun Dec 19th, 2021 at 09:31:36 PM EST
[ Parent ]
Re: The Pandemic Experiment of Trial and Error (none / 0)
Fauci says omicron variant is 'just RAGING around the world'
"the real problem" for the U.S. hospital system is that "we have so many people in this country who are eligible to be vaccinated who have not yet been vaccinated." differential diagnoses and inadequate clinical therapies.
[...]
the country has been battered by an unrelenting waveCOVID-19 SARS-CoV-2 mutations and variations that have left many Americans emotionally exhausted, dispirited and worried about infections surviving COVID-19 health care in and discharge from hospital
wut
With the threat that rising infections could worsen the supply chain challenges facing the United States and fuel inflation, [said] Gov. Jared Polis, D-Colo.
wut
The administration is expecting a series of breakthrough [vaccine or antiviral] infections[!] with the surge of holiday travelers. Fauci said most people who have been vaccinated and gotten a booster should be fine if they take precautions
wut
Fauci told NBC he saw the variants coming and he thought [Kamala?!] Harris' statement "was taken a bit out of context," adding he believed she was referring to "the extraordinary number of mutations [alpha,  delta, gamma, lamda, omicron] ... particularly with omicron. No one had expected it that much but we were well-prepared and expected that we were going to see variants."
by Cat on Sun Dec 19th, 2021 at 10:46:01 PM EST
[ Parent ]
Losing It All - Dutch Covid Policy (none / 0)
Dutch Cooperation Made an 'Intelligent Lockdown' a Success | Bloomberg - June 5, 2020 |

Dutch Christmas Shopping Ends As Lockdown Returns

Dutch shopkeepers say Christmas lockdown has left them `broken' | The Guardian |

In a devastating blow to many Christmas plans, households are allowed only four visitors a day on Christmas Eve, Christmas Day, Boxing Day and 31 January and New Year's Day. Two visitors are permitted on other days.

The announcement on Saturday night by the prime minister, Mark Rutte, who had described the lockdown as "unavoidable" due to the wave of the Omicron Covid variant "bearing down", came ahead of what would be the biggest sales week for many shops.

....
Across Europe, governments are contemplating tougher restrictions in the light of the spread of the Omicron Covid variant, including in Italy.

In Belgium, where thousands of protesters demonstrated in central Brussels on Sunday for a third time against further restrictions, Christie Morreale, the minister for health in the Walloon region of Belgium, could only say a further lockdown was "not on the table for the government at this stage".

No leadership, poor decision making, slow implementation and execution, a long two year mess by Mark Rutte & Co. ... lockdown could have been avoided. This really hurts the middle class of The Netherlands.

'Sapere aude'

by Oui (Oui) on Sun Dec 19th, 2021 at 08:54:13 PM EST
Re: Latest COVID Trade War UPDATE (none / 1)
I've noted with interest disturbances in NPI crisis management, broadcast sotto voce by the press corpse. These are, incremental shifts in emphasis from eradicating The One pathogen (beside CHINA) threatening civilization to a process of attenuating myriad active, "off-label" ingredients used to treat "moderate and severe" double "pneumonia-like" symptoms to "promising," authorized, brand-name experimental immuno-modulating products that induce synthetic SARS-CoV-2 or bacterial antigens, rather than repair COVID-19 injuries and rehabilitate ADLs.

Omicron may sideline two leading drugs against COVID-19

For more than a year antibody drugs from Regeneron and Eli Lilly have been the go-to treatments for early COVID-19, thanks to their ability to head off severe disease and keep patients out of the hospital.
[...]
A third antibody from British drugmaker GlaxoSmithKline appears to be the best positioned to fight omicron. But Glaxo's drug is not widely available in the U.S., accounting for a small portion of the millions of doses purchased and distributed by the federal government. U.S. health officials are now rationing scarce drug supplies to states.

For the past 2 years, government PR communicated the singular measure of morbidity as presentation of the disease, COVID-19. Obversely, daily estimates of partial and full dosage, or aggregate uptake, of an extremely limited set of antiviral medication d/b/a SARS-CoV-2 vaccines have satisfied popular expectations of "herd immunity" derived from institutional compliance despite statistically insignificant reductions in rates SARS-CoV-2 mutations, variants' "transmissibility," and death attributed either to grave dangers of non-compliance alone. "Vulnerability" masks "pre-existing conditions," excluding contraindicated pharmacology. Never serial infection ("breakthrough vaccine" cases). Never clinical incompetence.

NEVERTHELESS, observations such as supply chain failures (Q attenuated test devices, Q clinical personnel, Big Data std deviations, val + vol mRNA inventory, R&D, useful life), and authoritative controversies (political and clinical) continue to confound the predictive power of pharmaceutical agents (political and chemical) and furnish much larger markets populated by the living, ("long" or "recovered") COVID-19 "consumer-patients," already captured by multiple maintenance drug regimen "pharmacokinetics".

In Clinical Care, What Will Amazon Deliver?

Public education in healthcare offered by paid "social media" has well and truly undermined the credibility of industrial medicine as advertised, while contributing to GDP dominated by self-service economies of scale.
archived single point of pharma mRNA engineered FAILURE, Fri Nov 5th, 2021, Wed Sep 8th, 2021

by Cat on Sun Dec 19th, 2021 at 08:59:00 PM EST
programmed for failure (none / 0)
Fauci: RECORD coronavirus DEATHS in US From [OR WITH?] omicron likely, sez the failed infectious diseases expert, from HIV to present
"We definitely saw variants coming. I think what one referred to, what was not anticipated was the extent of the mutations and the amino acid [ACE-*] substitutions in omicron, which is really unprecedented," Fauci said. "It kind of came out of nowhere, where you have a virus that has 50 mutations, 30 of which are in the spike protein and 10 or 12 of which are in the receptor binding domain. I mean, to me, that's really quite unprecedented."
wut dat 3CL protease inhibitor
by Cat on Sun Dec 19th, 2021 at 10:14:22 PM EST
[ Parent ]
when all you've got is a hammer ... (none / 0)
by Cat on Sun Dec 19th, 2021 at 10:15:37 PM EST
[ Parent ]
Dutch Doctors Prescribe Ivermectin (none / 0)
Even a large minority believe in conspiracies .... and Trump!

Online doctors giving ivermectin to Covid patients; Investigation launched

The Health and Youth Care Inspectorate (IGJ) is investigating a group of doctors who prescribed the controversial drug Ivermectin to people with Covid-19. The Inspectorate confirmed this on Tuesday after reporting by RTL Nieuws. It is not recommended to use Ivermectin in the treatment of Covid-19. The drug is used to treat parasites, for example, scabies, not viruses.

Chief Inspector Roderick Runne said he understands that people are looking for good treatment for Covid-19. "But that's not Ivermectin. Doctors should inform their patients about it and certainly not prescribe it." The Inspectorate said it will tackle doctors and pharmacists who still provide the drug to patients with the coronavirus.

Thailand Ivermectin Clinical Trial | Gates Foundation - May 2020 |

'Sapere aude'

by Oui (Oui) on Wed Dec 22nd, 2021 at 06:31:18 PM EST
Re: Dutch Doctors Prescribe Ivermectin (none / 1)
Der Postilon
Der Schul-Tiermedizin schenkt sie keinen Glauben mehr: Die österreichische Vollblutstute Anka, die derzeit unter Wurmbefall leidet, hat sich heute mit dem Wirkstoff Comirnaty der Firma BioNTech impfen lassen lassen. In den letzten Wochen wird die eigentlich zur Eindämmung der Corona-Pandemie entwickelte Impfung von immer mehr Querdenker-Pferden als Heilmittel gegen Würmer angepriesen.
by gk (gk (gk quattro due due sette @gmail.com)) on Wed Dec 22nd, 2021 at 06:46:09 PM EST
[ Parent ]
Latest Data Omicron Variant | 155 comments (155 topical, 0 editorial, 0 hidden)


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